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在学术医疗中心中,临床亚专科在痴呆的门诊评估和治疗方面存在差异。

Differences between clinical subspecialties in the outpatient evaluation and treatment of dementia in an academic medical center.

机构信息

Department of Neurology, Michael E. DeBakey VA Medical Center, Houston, Tex., USA.

出版信息

Dement Geriatr Cogn Disord. 2010;29(1):28-36. doi: 10.1159/000254701. Epub 2010 Jan 27.

Abstract

BACKGROUND

Professional organizations have recommended guidelines for the optimal investigation and management of dementia. It is unknown whether physicians from different subspecialties investigate and treat dementia in the same manner or according to these guidelines.

METHODS

We screened 1,401 charts of patients who were seen in neurology, mental health, geropsychiatry and geriatrics clinics. The charts of 410 patients who were diagnosed with dementia were reviewed in detail to determine how they were evaluated and managed.

RESULTS

Overall, 40% of patients received a complete laboratory workup to rule out comorbidities, 70% of patients received neuroimaging with either computerized tomography or magnetic resonance imaging of the brain, 63% had a depression screen and 38% of patients underwent neuropsychological testing. However, the frequency with which they were obtained differed significantly across clinics (p < 0.05). The frequency with which acetylcholinesterase inhibitors (CHEIs) were used did not differ significantly (p = 0.07) for patients with Alzheimer's disease (AD), but differed significantly (p < 0.05) for dementia categories where CHEIs are thought to be useful (AD, vascular dementia and dementia with Lewy bodies).

CONCLUSIONS

There were significant differences between subspecialties in the evaluation and treatment of dementia. It will be important to investigate whether these differences alter patient outcomes.

摘要

背景

专业组织已经为痴呆的最佳调查和管理推荐了指南。目前尚不清楚不同亚专业的医生是否以相同的方式或根据这些指南调查和治疗痴呆。

方法

我们筛选了在神经病学、心理健康、老年精神病学和老年医学诊所就诊的 1401 份患者病历。详细审查了 410 名被诊断为痴呆症的患者的病历,以确定他们的评估和管理方式。

结果

总体而言,40%的患者接受了全面的实验室检查以排除合并症,70%的患者接受了计算机断层扫描或脑磁共振成像的神经影像学检查,63%的患者接受了抑郁筛查,38%的患者接受了神经心理学测试。然而,它们在不同诊所的获取频率差异显著(p < 0.05)。乙酰胆碱酯酶抑制剂(CHEIs)在阿尔茨海默病(AD)患者中的使用频率差异无统计学意义(p = 0.07),但在认为 CHEIs 有用的痴呆症类别中差异显著(p < 0.05)(AD、血管性痴呆和路易体痴呆)。

结论

在痴呆的评估和治疗方面,各亚专业之间存在显著差异。研究这些差异是否会改变患者的预后将是很重要的。

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