Department of Otorhinolaryngology, Santa Croce Hospital, Fano, Italy.
Acta Otorhinolaryngol Ital. 2009 Apr;29(2):108-13.
Cogan's syndrome is defined as a chronic inflammatory disease of unknown origin, an autoimmune disease, characterized by bilateral sensorineural hearing loss, vestibular symptoms, inflammatory ocular manifestations with variable risk of developing into a systemic disease. The onset of disease is variable but is often characterized by isolated ocular symptoms or acute ear and/or vestibular manifestations, variably associated. The diagnosis of Cogan's syndrome can be a challenge as is evident in the case described here since it is based only on the association between bilateral ocular and vestibuloauditory symptoms with no specific diagnostic tests available.
Cogan 综合征定义为原因不明的慢性炎症性疾病、自身免疫性疾病，其特征为双侧感觉神经性听力损失、前庭症状、眼部炎症表现，具有发展为全身性疾病的不同风险。疾病的发病是多变的，但通常表现为孤立的眼部症状或急性耳和/或前庭表现，不同程度地相关。Cogan 综合征的诊断具有挑战性，正如这里描述的病例所示，因为它仅基于双侧眼部和前庭听觉症状之间的关联，而没有可用的特定诊断测试。
