Tareen Basir, Godoy Guilherme, Taneja Samir S
Rev Urol. 2009 Fall;11(4):203-12.
Focal therapy has been proposed in recent years as a means of bridging the gap between radical prostatectomy and active surveillance for treatment of prostate cancer. The rationale for focal therapy comes from its success in treating other malignancies. One of the challenges in applying such an approach to the treatment of prostate cancer has been the multifocal nature of the disease. This review addresses the selection of potentially ideal candidates for focal therapy and discusses which modalities are currently being used and proposed for focal therapy. Setting and meeting guidelines for oncologic efficacy is a challenge we must embrace to safely deliver this potentially revolutionary approach to treating men with prostate cancer.
近年来，聚焦治疗被提议作为一种在前列腺癌根治术和积极监测之间架起桥梁的治疗手段。聚焦治疗的理论依据源于其在治疗其他恶性肿瘤方面的成功。将这种方法应用于前列腺癌治疗的挑战之一在于该疾病的多灶性本质。这篇综述探讨了聚焦治疗潜在理想候选者的选择，并讨论了目前正在使用以及提议用于聚焦治疗的方式。设定并满足肿瘤学疗效的指导原则是我们必须接受的一项挑战，以便安全地将这种可能具有革命性的前列腺癌治疗方法应用于男性患者。
