Département de Biologie, Faculté de Sciences, Université de Sherbrooke, 2500 Boulevard de l'Uni-versité, Sherbrooke, Québec J1K 2R1, Canada.
Pacific Agri-Food Research Centre, Agriculture and Agri-Food Canada, P.O. Box 1000, Agassiz, BC V0M 1A0, Canada.
Int J Mol Sci. 2009 Jul 31;10(8):3400-3419. doi: 10.3390/ijms10083400.
To protect themselves, plants accumulate an armoury of antimicrobial secondary metabolites. Some metabolites represent constitutive chemical barriers to microbial attack (phytoanticipins) and others inducible antimicrobials (phytoalexins). They are extensively studied as promising plant and human disease-controlling agents. This review discusses the bioactivity of several phytoalexins and phytoanticipins defending plants against fungal and bacterial aggressors and those with antibacterial activities against pathogens affecting humans such as Pseudomonas aeruginosa and Staphylococcus aureus involved in respiratory infections of cystic fibrosis patients. The utility of plant products as "antibiotic potentiators" and "virulence attenuators" is also described as well as some biotechnological applications in phytoprotection.
为了保护自身，植物积累了大量抗菌的次生代谢物。一些代谢物是对微生物攻击的组成性化学屏障（植物抗毒素），而另一些则是诱导性抗菌物质（植物防御素）。它们作为有前途的植物和人类疾病控制剂而被广泛研究。本文综述了几种植物抗毒素和植物抗毒素的生物活性，这些物质可以防御植物免受真菌和细菌的侵害，并且具有抗菌活性，可以对抗影响人类的病原体，如铜绿假单胞菌和金黄色葡萄球菌，它们与囊性纤维化患者的呼吸道感染有关。本文还描述了植物产物作为“抗生素增效剂”和“毒力减毒剂”的用途，以及在植物保护中的一些生物技术应用。
