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一项前瞻性、对比性队列研究,比较鼻造影、鼻-鼻窦结局测试-20和健康相关生活质量问卷。

Prospective, comparative, cohort study comparing the rhinogram, Sino-Nasal Outcome Test-20 and Heath-Related Quality of Life questionnaire.

作者信息

Patel Parag M, Maskell S, Heywood R, Eze N, Hern J

机构信息

Department of ENT, Frimley Park Hospital, Camberley, UK.

出版信息

J Laryngol Otol. 2010 Jun;124(6):623-30. doi: 10.1017/S0022215109992805. Epub 2010 Feb 1.

DOI:10.1017/S0022215109992805
PMID:20113535
Abstract

BACKGROUND

Many outcome measures exist for rhinosinusitis. However, few are used in the clinical setting due to their long completion times.

OBJECTIVE

To assess the validity, reliability and responsiveness of the rhinogram, compared with two validated rhinosinusitis outcome measures: the Sino-Nasal Outcome Test-20 and the Heath-Related Quality of Life questionnaire.

METHODS

Fifty-one patients were entered into a prospective, comparative, cohort study using all three outcome measures one week pre-operatively and three months post-operatively. Outcome scores were then correlated using non-parametric Spearman's rank correlation and chi-square testing for the diagnostic criteria of all three outcome measures.

RESULTS

Statistically significant correlations were found between all three outcome measures for all symptom scores, individually as well as combined (p < 0.01 for all calculations). Comparison of the diagnostic accuracy of the rhinogram, compared with the Sino-Nasal Outcome Test-20 and the Heath-Related Quality of Life questionnaire, showed statistical significance (p < 0.05; chi-square test).

CONCLUSION

The rhinogram is a reliable, valid and responsive rhinosinusitis outcome measure which can assist patient diagnosis and management in the clinical setting. Due to its quick completion time, this outcome measure could be used in rhinology out-patient clinics.

摘要

背景

鼻窦炎有多种结局指标。然而,由于完成时间长,很少在临床中使用。

目的

与两种经过验证的鼻窦炎结局指标(鼻窦结局测试-20和健康相关生活质量问卷)相比,评估鼻造影的有效性、可靠性和反应性。

方法

51例患者参与一项前瞻性、比较性队列研究,在术前一周和术后三个月使用所有三种结局指标。然后使用非参数Spearman等级相关性和卡方检验对所有三种结局指标的诊断标准进行结局评分相关性分析。

结果

所有三种结局指标的所有症状评分,单独及合并分析时均发现具有统计学意义的相关性(所有计算p<0.01)。与鼻窦结局测试-20和健康相关生活质量问卷相比,鼻造影诊断准确性的比较显示具有统计学意义(p<0.05;卡方检验)。

结论

鼻造影是一种可靠、有效且具有反应性的鼻窦炎结局指标,可在临床环境中辅助患者诊断和管理。由于其完成时间短,该结局指标可用于鼻科门诊。

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