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长期锂治疗停止后并发谵妄的躁狂。

Mania complicated with delirium following cessation of long-term lithium therapy.

机构信息

Department of Psychiatry, Tri-Service General Hospital, Neihu District, Taipei 114, Taiwan.

出版信息

Gen Hosp Psychiatry. 2010 Jan-Feb;32(1):102-4. doi: 10.1016/j.genhosppsych.2009.09.003. Epub 2009 Oct 20.

DOI:10.1016/j.genhosppsych.2009.09.003
PMID:20114136
Abstract

OBJECTIVE

To highlight the association between the use of lithium and the development of delirium following discontinuation of lithium therapy, a condition that substantially increases the risk of psychogenic events and other medical complications.

METHOD

Physical examination, laboratory studies including measurement of serum calcium and parathyroid hormone levels, measurement of urine osmolalities before and after desmopressin administration and a brain magnetic resonance imaging.

RESULTS

A 49-year-old woman with a background history of bipolar disorder taking lithium presented with severe mania complicated with delirium following discontinuation of lithium therapy.

CONCLUSION

Mania in the context of lithium therapy may be complicated with delirium. Therefore, mental status should be closely monitored in patients receiving lithium in order to facilitate early detection and intervention of delirium to prevent further health complications.

摘要

目的

强调锂的使用与锂治疗停药后谵妄的发生之间的关联,这种情况大大增加了精神源性事件和其他医疗并发症的风险。

方法

体格检查、实验室研究,包括血清钙和甲状旁腺激素水平的测量、去氨加压素给药前后尿渗透压的测量以及脑部磁共振成像。

结果

一名 49 岁的女性,有双相情感障碍的背景病史,正在服用锂,锂治疗停药后出现严重躁狂症并发谵妄。

结论

锂治疗期间的躁狂症可能并发谵妄。因此,在给锂治疗的患者中,应密切监测精神状态,以便及早发现和干预谵妄,防止进一步的健康并发症。

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