Gaini Renato Maria, Romagnoli Marco, Sala Alessandra, Garavello Werner
Department of Otorhinolaryngology-Head and Neck Surgery, University of Milano-Bicocca, DNTB, Monza, Italy.
Int J Pediatr Otorhinolaryngol. 2009 Dec;73 Suppl 1:S65-70. doi: 10.1016/S0165-5876(09)70013-8.
Cancer among children is relatively uncommon, with approximately 1 in 7,000 children 0 to 14 years of age being newly diagnosed each year in the United States, and Hodgkin and non-Hodgkin's lymphomas constitute 10-15% of all childhood cancers in the more developed countries, after acute leukemias and brain tumors. The diagnosis of lymphoma frequently involves otolaryngologists that play also an important role in the its management. A high index of suspicion for lymphoma as a cause of complaints in the head and neck region can lead an early diagnosis and improved outcome for lymphomas. This article reviews the epidemiology, presentation, diagnosis, staging, treatment and prognosis of Hodgkin and non-Hodgkin's lymphomas in children.
儿童癌症相对不常见，在美国，每年每7000名0至14岁的儿童中约有1人被新诊断出患有癌症，在较发达国家，霍奇金淋巴瘤和非霍奇金淋巴瘤在所有儿童癌症中占10%-15%，仅次于急性白血病和脑肿瘤。淋巴瘤的诊断常常涉及耳鼻喉科医生，他们在淋巴瘤的治疗中也发挥着重要作用。对头颈部区域症状起因高度怀疑为淋巴瘤可实现早期诊断并改善淋巴瘤的治疗结果。本文综述了儿童霍奇金淋巴瘤和非霍奇金淋巴瘤的流行病学、临床表现、诊断、分期、治疗及预后。
