de Carvalho Guilherme-Machado, Pauna Henrique-Furlan, Crespo Agrício-Nubiato, Gusmão Reinaldo-Jordão, Guimarães Alexandre-Caixeta
Department of Otorhinolaryngology, Head and Neck Surgery, University of Campinas, Campinas, São Paulo, Brazil.
Iran J Otorhinolaryngol. 2018 Mar;30(97):69-75.
Lymphoma is a common malignant tumor of the head and neck occurring during childhood. Early diagnosis is very important in terms of prognosis in patients with tonsillar lymphoma.Our objective was to evaluate the clinical manifestations of pediatric tonsillar lymphoma according to different age groups.
A systematic review of available English, Spanish, or Portuguese literature from January 1996 to June 2012 was performedin the BIREME, Cochrane, IBECS, Lilacs, PubMed/Medline, SCIELO, and Scopus databases, using "tonsillar lymphoma" and "children" as keywords. Inclusion criteria were pediatric case reports, patients aged up to 18 years, and information on clinical features at the time of diagnosis.
Out of 87 identified publications, 13 articles were selected describing 53 patients. Tonsillar asymmetry was the most common sign. Snoring is a common sign in patients aged under 5 years; clinical lymphadenopathy is frequent among patients aged between 6 and 10 years; and dysphagia is a common sign in patients between 11 and 18 years of age. Burkitt's lymphoma is the most common form among all ages studied, followed by B-cell lymphoma.
Clinical manifestations differ according to age group. However, tonsillar asymmetry is the most frequent sign regardless of age group.
淋巴瘤是儿童期常见的头颈部恶性肿瘤。对于扁桃体淋巴瘤患者而言，早期诊断对预后非常重要。我们的目的是根据不同年龄组评估儿童扁桃体淋巴瘤的临床表现。
在BIREME、Cochrane、IBECS、Lilacs、PubMed/Medline、SCIELO和Scopus数据库中，使用“扁桃体淋巴瘤”和“儿童”作为关键词，对1996年1月至2012年6月期间可用的英文、西班牙文或葡萄牙文文献进行系统综述。纳入标准为儿童病例报告、18岁及以下患者以及诊断时的临床特征信息。
在87篇已识别的出版物中，选择了13篇文章，描述了53例患者。扁桃体不对称是最常见的体征。打鼾是5岁以下患者的常见体征；临床淋巴结病在6至10岁患者中很常见；吞咽困难是11至18岁患者的常见体征。在所有研究年龄组中，伯基特淋巴瘤是最常见的类型，其次是B细胞淋巴瘤。
临床表现因年龄组而异。然而，无论年龄组如何，扁桃体不对称是最常见的体征。
