Quintiliani R, Nightingale C H
Division of Infectious Diseases/Allergy-Immunology, Hartford Hospital, Connecticut.
Pharmacotherapy. 1991;11(1 ( Pt 2)):6S-13S.
In an effort to remedy inappropriate and excessive use of antimicrobials and to control costs, most hospitals have developed some type of antimicrobial management program. At Hartford Hospital, our most effective approaches have been those that reduce the chances for physician error, decrease the burden on ancillary services, and encourage short hospital stays. These include automatic correction of dose and dosing intervals of antimicrobials and, if possible, their conversion by pharmacy to cost-effective alternative agents; daily review of patients who are taking the drugs by an antimicrobial team; and replacement of parenteral with oral agents as soon as possible. Physician acceptance of these approaches will require significant changes in traditional prescribing styles and willingness to allow pharmacists to implement the recommendations of therapeutic and medical staff committees.
为了纠正抗菌药物的不当和过度使用并控制成本，大多数医院都制定了某种类型的抗菌药物管理计划。在哈特福德医院，我们最有效的方法是那些减少医生出错几率、减轻辅助科室负担并鼓励缩短住院时间的方法。这些方法包括自动纠正抗菌药物的剂量和给药间隔，并且如果可能的话，由药房将其转换为具有成本效益的替代药物；抗菌药物团队每天对正在使用这些药物的患者进行评估；以及尽快用口服药物替代注射用药物。医生接受这些方法将需要传统处方方式有重大改变，并且愿意让药剂师实施治疗和医务人员委员会的建议。
