Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
J Am Acad Dermatol. 2010 Feb;62(2):191-202, quiz 203-4. doi: 10.1016/j.jaad.2009.10.031.
Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the paucity of randomized, double-blind, placebo-controlled studies make the evidence-based assessment of these therapies difficult. The second part of this two-part series on AA discusses treatment options in detail and suggests treatment plans according to specific disease presentation. It also reviews recently reported experimental treatment options and potential directions for future disease management.
After completing this learning activity, participants should be able to compare the efficacy and safety of various treatment options, formulate a treatment plan tailored to individual patients, and recognize recently described treatments and potential therapeutic approaches.
已描述了各种治疗药物来治疗斑秃(AA),但均无根治或预防作用。AA 的治疗目的是抑制疾病活动。高自发缓解率和缺乏随机、双盲、安慰剂对照研究使得这些疗法的循证评估变得困难。本 AA 两部分系列的第二部分详细讨论了治疗选择,并根据特定疾病表现提出了治疗计划。它还回顾了最近报道的实验治疗选择和未来疾病管理的潜在方向。
完成本学习活动后,参与者应能够比较各种治疗选择的疗效和安全性,为个体患者制定量身定制的治疗计划,并认识到最近描述的治疗方法和潜在的治疗方法。