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二苯环丙烯酮治疗斑秃。

DPCP for the treatment of alopecia areata.

作者信息

Bolduc C, Shapiro J

机构信息

Division of Dermatology, Faculty of Medicine, University of British Columbia, Vancouver, Canada.

出版信息

Skin Therapy Lett. 2000;5(5):3-4.

PMID:10854342
Abstract

Topical immunotherapy with diphencyprone (DPCP) for the treatment of severe alopecia areata has been used since 1983 and is felt to be the treatment of choice by many dermatologists. Although there have been no major side effects reported since its initial use, there remain some unknowns regarding its safety. Because DPCP has at least a 40% success rate for cosmetically acceptable regrowth in extensive alopecia areata, its availability is an important matter for patients with alopecia areata.

摘要

自1983年以来,二苯环丙烯酮(DPCP)局部免疫疗法一直用于治疗重度斑秃,许多皮肤科医生认为它是首选治疗方法。尽管自首次使用以来尚未报告有重大副作用,但其安全性仍存在一些未知因素。由于DPCP在广泛斑秃中实现外观上可接受的毛发再生的成功率至少为40%,因此其可用性对斑秃患者来说是一个重要问题。

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The use of topical diphenylcyclopropenone for the treatment of extensive alopecia areata.外用二苯环丙烯酮治疗广泛性斑秃。
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引用本文的文献

1
A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata.两种二苯环丙烯酮方案治疗顽固性斑秃疗效与安全性的回顾性对照研究
Dermatol Reports. 2017 Nov 30;9(2):7399. doi: 10.4081/dr.2017.7399. eCollection 2017 Oct 11.
2
Alopecia Areata: a Comprehensive Review of Pathogenesis and Management.斑秃:发病机制与治疗的全面综述。
Clin Rev Allergy Immunol. 2018 Feb;54(1):68-87. doi: 10.1007/s12016-017-8620-9.
3
Current treatment strategies in pediatric alopecia areata.
儿童斑秃的当前治疗策略。
Indian J Dermatol. 2012 Nov;57(6):459-65. doi: 10.4103/0019-5154.103066.
4
The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results.斑秃的C3H/HeJ小鼠和DEBR大鼠模型:临床前药物筛选方法及结果综述
Exp Dermatol. 2008 Oct;17(10):793-805. doi: 10.1111/j.1600-0625.2008.00773.x.