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斑秃管理现行国际指南比较——全面综述

Comparison of Current International Guidelines for the Management of Alopecia Areata-Comprehensive Review.

作者信息

Kropidłowska Julia, Kvinen Alexandra, Lewandowski Miłosz, Nowicki Roman J, Barańska-Rybak Wioletta

机构信息

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.

Practical and Experimental Dermatology Student Scientific Association, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.

出版信息

Int J Mol Sci. 2025 Sep 4;26(17):8632. doi: 10.3390/ijms26178632.

Abstract

Alopecia areata is a persistent autoimmune-mediated disease with a complicated pathophysiology and a prevalence of approximately 2%. The exact pathogenesis is yet to be identified; nevertheless, environmental factors, autoimmune mechanisms and genetic factors among others all contribute to the multifactorial etiopathogenesis of the disease. Even though alopecia areata is frequently self-limiting and recovery can occur on its own, it can cause esthetic challenges that might precipitate psychosocial disorders. This article aims to provide a clinical update on alopecia areata comparing the most important international guidelines, with particular emphasis on current treatment options and comorbidities.

摘要

斑秃是一种持续的自身免疫介导性疾病,其病理生理学复杂,患病率约为2%。确切的发病机制尚未明确;然而,环境因素、自身免疫机制和遗传因素等都促成了该疾病的多因素病因。尽管斑秃通常具有自限性,可自行恢复,但它会引发美观问题,可能导致心理社会障碍。本文旨在提供斑秃的临床最新情况,比较最重要的国际指南,尤其着重于当前的治疗选择和合并症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cf/12429261/878c14a52fa9/ijms-26-08632-g001.jpg

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