Kropidłowska Julia, Kvinen Alexandra, Lewandowski Miłosz, Nowicki Roman J, Barańska-Rybak Wioletta
Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.
Practical and Experimental Dermatology Student Scientific Association, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.
Int J Mol Sci. 2025 Sep 4;26(17):8632. doi: 10.3390/ijms26178632.
Alopecia areata is a persistent autoimmune-mediated disease with a complicated pathophysiology and a prevalence of approximately 2%. The exact pathogenesis is yet to be identified; nevertheless, environmental factors, autoimmune mechanisms and genetic factors among others all contribute to the multifactorial etiopathogenesis of the disease. Even though alopecia areata is frequently self-limiting and recovery can occur on its own, it can cause esthetic challenges that might precipitate psychosocial disorders. This article aims to provide a clinical update on alopecia areata comparing the most important international guidelines, with particular emphasis on current treatment options and comorbidities.
斑秃是一种持续的自身免疫介导性疾病，其病理生理学复杂，患病率约为2%。确切的发病机制尚未明确；然而，环境因素、自身免疫机制和遗传因素等都促成了该疾病的多因素病因。尽管斑秃通常具有自限性，可自行恢复，但它会引发美观问题，可能导致心理社会障碍。本文旨在提供斑秃的临床最新情况，比较最重要的国际指南，尤其着重于当前的治疗选择和合并症。
