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[危重症患者的微循环改变:病理生理学、监测与治疗]

[Microcirculatory alterations in critically ill patients: pathophysiology, monitoring and treatments].

作者信息

Siegenthaler N, Giraud R, Piriou V, Romand J-A, Bendjelid K

机构信息

Service des soins intensifs, faculté de médecine de Genève, hôpitaux universitaires de Genève, Genèva 14, Switzerland.

出版信息

Ann Fr Anesth Reanim. 2010 Feb;29(2):135-44. doi: 10.1016/j.annfar.2009.10.023. Epub 2010 Jan 29.

Abstract

Microcirculation represents a complex system devoted to provide optimal tissue substrates and oxygen. Therefore, pathophysiological and technological knowledge developments tailored for capillary circulation analysis should generate major advances for critically ill patients' management. In the future, microcirculatory monitoring in several critical care situations will allow recognition of macro-microcirculatory decoupling, and, hopefully, it will promote the use of treatments aimed at preserving tissue oxygenation and substrate delivery.

摘要

微循环是一个致力于提供最佳组织底物和氧气的复杂系统。因此,针对毛细血管循环分析的病理生理学和技术知识的发展应为危重症患者的管理带来重大进展。未来,在多种重症监护情况下进行微循环监测将有助于识别宏观-微循环解耦,并且有望促进旨在维持组织氧合和底物输送的治疗方法的应用。

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