Laboratoire de Psychiatrie and EA 4139, Université Victor Segalen Bordeaux 2, INSERM-IFR-99, Bordeaux, France (EU).
J Subst Abuse Treat. 2010 Apr;38(3):220-30. doi: 10.1016/j.jsat.2009.12.003. Epub 2010 Feb 8.
Our objective was to evaluate the prevalence and temporal sequence of co-occurrence of anxiety disorders with opiate dependence in order to better define the relationship between these two disorders and to improve diagnosis and treatment. The search used Medline and Toxibase up to January 1, 2009, and was based on a systematic review method. Eighteen studies were found. Prevalence of anxiety disorders assessed by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria was high in opiate-dependent treated persons (lifetime prevalence ranged from 26% to 35%). Among anxiety disorders, phobic disorders have been shown to often precede the onset of opiate dependence. The identification of substance-induced versus independent anxiety disorder has important treatment implication. The monitoring of anxiety symptoms after several weeks of abstinence may allow physicians to determine the relationship between dependence and anxiety and make a reliable diagnosis of any initial anxious disorder. Specific management of anxiety disorder may then be used.
我们的目的是评估焦虑障碍与阿片类药物依赖共病的发生率和时间顺序，以便更好地定义这两种疾病之间的关系，并改善诊断和治疗。检索使用了 Medline 和 Toxibase，截至 2009 年 1 月 1 日，并基于系统评价方法。发现了 18 项研究。根据精神疾病诊断与统计手册第四版（DSM-IV）标准评估的阿片类药物依赖治疗者的焦虑障碍发生率较高（终身患病率范围为 26%至 35%）。在焦虑障碍中，恐惧症已被证明经常先于阿片类药物依赖的发生。确定物质引起的焦虑障碍与独立的焦虑障碍具有重要的治疗意义。在戒断数周后监测焦虑症状可以让医生确定依赖和焦虑之间的关系，并对任何初始焦虑障碍做出可靠的诊断。然后可以使用特定的焦虑障碍管理方法。
