MRC Centre for Neuropsychiatric Genetics and Genomics, Henry Wellcome Building, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.
Br J Psychiatry. 2010 Feb;196(2):92-5. doi: 10.1192/bjp.bp.109.073429.
Recent genetic studies reinforce the view that current approaches to the diagnosis and classification of major psychiatric illness are inadequate. These findings challenge the distinction between schizophrenia and bipolar disorder, and suggest that more attention should be given to the relationship between the functional psychoses and neurodevelopmental disorders such as autism. We are entering a transitional period of several years during which psychiatry will need to move from using traditional descriptive diagnoses to clinical entities (categories and/or dimensions) that relate more closely to the underlying workings of the brain.
最近的遗传学研究进一步证实,目前用于主要精神疾病的诊断和分类的方法并不完善。这些发现对精神分裂症和双相情感障碍之间的区别提出了挑战,并表明应该更加关注功能性精神疾病和神经发育障碍(如自闭症)之间的关系。我们正进入一个过渡时期,在这几年中,精神病学将需要从使用传统的描述性诊断转变为与大脑的内在运作更相关的临床实体(类别和/或维度)。