Serdiuk T M, Grinevich L I
Vrach Delo. 1991 Jan(1):42-4.
Cellular and humoral immunity was investigated in practically healthy subjects with PLM allele subtypes in the homozygotic form, PiM3M3 phenotypical variants and normal phenotypical variant PiM1M1 in the presence of which practically healthy subjects show a 100% antitryptic activity in the blood serum. A study of the immunological reactivity of 225 patients with chronic obstructive bronchitis revealed in these patients disorders of the cellular and humoral immunity and they were more pronounced in patients with PiM3M3 phenotypical variant.
在纯合形式的PLM等位基因亚型、PiM3M3表型变异体以及正常表型变异体PiM1M1的实际健康受试者中研究了细胞免疫和体液免疫，在这些实际健康受试者中，血清显示出100%的抗胰蛋白酶活性。对225例慢性阻塞性支气管炎患者的免疫反应性研究发现，这些患者存在细胞免疫和体液免疫紊乱，且在PiM3M3表型变异体患者中更为明显。
