[State of anti-infection defense in patients with chronic bronchitis].

Cellular and humoral antiinfection defense, frequency and severity of microbial infection were evaluated in patients with chronic nonobstructive and obstructive bronchitis. Systemic approach and analysis demonstrated that in chronic bronchitis there appeared shifts in cellular and humoral defense, functional dissociation of the above parameters, defects in intra- and intersystem compensation. Thus, in chronic bronchitis antiinfection defense needs immunocorrective therapy which is especially appropriate in bronchial obstruction and persistent infection of peripheral blood.