鲁米纳内酯，一种从石皮珊瑚藻中提取的用于石珊瑚幼虫的新型变态增强大环二萜内酯。
Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae.
作者信息
Kitamura Makoto, Schupp Peter J, Nakano Yoshikatsu, Uemura Daisuke
机构信息
Department of Biosciences and Informatics, Center for Biosciences and Informatics, Keio University, Hiyoshi, Yokohama 223-8522, Japan.
出版信息
Tetrahedron Lett. 2009 Nov 25;50(47):6606. doi: 10.1016/j.tetlet.2009.09.065.
Abstract
A new metamorphosis-enhancing macrodiolide, luminaolide (1), was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldii. Its structure was determined by spectroscopic analysis. A fraction (1.30 mug/mL) eluted with 80% aqueous MeOH by ODS gel column chromatography of the same CCA extract induced larval metamorphosis (25.9 +/- 7.4%) against Leptastrea purpurea, and its metamorphosis-inducing activity was further enhanced to 92.6 +/- 2.9% with the addition of 1 (25.6 ng/mL).
摘要
从石状珊瑚藻（CCA）红鲍氏石枝藻中分离出一种新的促进变态的大环二醇类化合物，即发光内酯（1）。通过光谱分析确定了其结构。用相同的CCA提取物进行ODS凝胶柱色谱法，以80%甲醇水溶液洗脱得到的一个馏分（1.30微克/毫升）可诱导紫斑细指海葵幼虫变态（25.9±7.4%），加入1（25.6纳克/毫升）后其变态诱导活性进一步提高到92.6±2.9%。
相似文献
1
Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae.鲁米纳内酯，一种从石皮珊瑚藻中提取的用于石珊瑚幼虫的新型变态增强大环二萜内酯。
Tetrahedron Lett. 2009 Nov 25;50(47):6606. doi: 10.1016/j.tetlet.2009.09.065.
2
Crustose coralline algae and a cnidarian neuropeptide trigger larval settlement in two coral reef sponges.壳状珊瑚藻和刺胞动物神经肽触发两种珊瑚礁海绵的幼虫附着。
PLoS One. 2012;7(1):e30386. doi: 10.1371/journal.pone.0030386. Epub 2012 Jan 25.
3
Coral larval settlement induction using tissue-associated and exuded coralline algae metabolites and the identification of putative chemical cues.利用组织相关和分泌的珊瑚藻代谢物诱导珊瑚幼虫附着，并鉴定可能的化学线索。
Proc Biol Sci. 2023 Oct 25;290(2009):20231476. doi: 10.1098/rspb.2023.1476. Epub 2023 Oct 18.
4
Enzymatic Characterization of the Morphogen Recognized by Agaricia humilis (Scleractinian Coral) Larvae.被矮小鹿角珊瑚（石珊瑚）幼虫识别的形态发生素的酶学特性
Biol Bull. 1991 Aug;181(1):104-122. doi: 10.2307/1542493.
5
Ocean acidification reduces induction of coral settlement by crustose coralline algae.海洋酸化降低了有孔虫藻对珊瑚附着的诱导作用。
Glob Chang Biol. 2013 Jan;19(1):303-15. doi: 10.1111/gcb.12008. Epub 2012 Sep 25.
6
Species-Specific Differences in the Microbiomes and Organic Exudates of Crustose Coralline Algae Influence Bacterioplankton Communities.壳状珊瑚藻微生物群落和有机渗出物的物种特异性差异影响浮游细菌群落。
Front Microbiol. 2019 Nov 8;10:2397. doi: 10.3389/fmicb.2019.02397. eCollection 2019.
7
Bacterial Communities Associated With Healthy and Bleached Crustose Coralline Alga .与健康和白化的石枝藻相关的细菌群落
Front Microbiol. 2021 Jun 9;12:646143. doi: 10.3389/fmicb.2021.646143. eCollection 2021.
8
Neuroactive compounds induce larval settlement in the scleractinian coral Leptastrea purpurea.神经活性化合物诱导石珊瑚幼虫附着。
Sci Rep. 2019 Feb 19;9(1):2291. doi: 10.1038/s41598-019-38794-2.
9
Elevated seawater temperature causes a microbial shift on crustose coralline algae with implications for the recruitment of coral larvae.海水温度升高导致皮壳状珊瑚藻的微生物群落发生变化，这可能对珊瑚幼虫的附着产生影响。
ISME J. 2011 Apr;5(4):759-70. doi: 10.1038/ismej.2010.152. Epub 2010 Oct 14.
10
Hierarchical settlement behaviours of coral larvae to common coralline algae.珊瑚幼虫对常见珊瑚藻的分层沉降行为。
Sci Rep. 2023 Apr 9;13(1):5795. doi: 10.1038/s41598-023-32676-4.
引用本文的文献
1
Cycloprodigiosin: A multispecies settlement cue for scleractinian coral larvae.环丙地嗪：一种用于石珊瑚幼虫的多物种定居信号。
Sci Rep. 2025 Jul 25;15(1):27075. doi: 10.1038/s41598-025-12409-5.
2
Microbiome Dynamics in Early Life Stages of the Precious Mediterranean Red Coral Corallium rubrum.珍贵的地中海红珊瑚红珊瑚早期生命阶段的微生物群落动态
Environ Microbiol Rep. 2025 Jun;17(3):e70127. doi: 10.1111/1758-2229.70127.
3
Linking differences in microbial network structure with changes in coral larval settlement.将微生物网络结构的差异与珊瑚幼虫附着的变化联系起来。
ISME Commun. 2023 Oct 21;3(1):114. doi: 10.1038/s43705-023-00320-x.
4
Coral larval settlement induction using tissue-associated and exuded coralline algae metabolites and the identification of putative chemical cues.利用组织相关和分泌的珊瑚藻代谢物诱导珊瑚幼虫附着，并鉴定可能的化学线索。
Proc Biol Sci. 2023 Oct 25;290(2009):20231476. doi: 10.1098/rspb.2023.1476. Epub 2023 Oct 18.
5
Photodegradation of a bacterial pigment and resulting hydrogen peroxide release enable coral settlement.细菌色素的光降解和由此产生的过氧化氢释放使珊瑚定居。
Sci Rep. 2023 Mar 2;13(1):3562. doi: 10.1038/s41598-023-30470-w.
6
Coral larval settlement preferences linked to crustose coralline algae with distinct chemical and microbial signatures.珊瑚幼虫的附着偏好与具有独特化学和微生物特征的壳状珊瑚藻有关。
Sci Rep. 2021 Jul 16;11(1):14610. doi: 10.1038/s41598-021-94096-6.
7
Marine-Derived Macrolides 1990-2020: An Overview of Chemical and Biological Diversity.海洋来源大环内酯类化合物 1990-2020：化学和生物多样性概述。
Mar Drugs. 2021 Mar 25;19(4):180. doi: 10.3390/md19040180.
8
Settlement of larvae from four families of corals in response to a crustose coralline alga and its biochemical morphogens.幼虫在有壳质珊瑚藻及其生物化学形态发生素的条件下，来自四个珊瑚科的定居。
Sci Rep. 2020 Oct 2;10(1):16397. doi: 10.1038/s41598-020-73103-2.
9
A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products.基于卷积神经网络的方法用于快速注释分子多样的天然产物。
J Am Chem Soc. 2020 Mar 4;142(9):4114-4120. doi: 10.1021/jacs.9b13786. Epub 2020 Feb 21.
10
Species-Specific Differences in the Microbiomes and Organic Exudates of Crustose Coralline Algae Influence Bacterioplankton Communities.壳状珊瑚藻微生物群落和有机渗出物的物种特异性差异影响浮游细菌群落。
Front Microbiol. 2019 Nov 8;10:2397. doi: 10.3389/fmicb.2019.02397. eCollection 2019.
本文引用的文献
1
Enzymatic Characterization of the Morphogen Recognized by Agaricia humilis (Scleractinian Coral) Larvae.被矮小鹿角珊瑚（石珊瑚）幼虫识别的形态发生素的酶学特性
Biol Bull. 1991 Aug;181(1):104-122. doi: 10.2307/1542493.
2
An Ancient Chemosensory Mechanism Brings New Life to Coral Reefs.一种古老的化学感应机制为珊瑚礁带来新的生机。
Biol Bull. 1996 Oct;191(2):149-154. doi: 10.2307/1542917.
3
Articulated coralline algae of the genus Amphiroa are highly effective natural inducers of settlement in the tropical abalone Haliotis asinina.艾氏角叉藻属的有节珊瑚藻是热带鲍鱼（皱纹盘鲍）附着的高效天然诱导物。
Biol Bull. 2008 Aug;215(1):98-107. doi: 10.2307/25470687.
4
Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "marinispora".马瑞诺霉素A - D，一种来自最近发现的“海孢子菌属”海洋放线菌的新型结构类别的抗肿瘤抗生素。
J Am Chem Soc. 2006 Feb 8;128(5):1622-32. doi: 10.1021/ja0558948.
5
Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria.从两个野外采集的海洋蓝细菌样本中分离出swinholide A及相关糖基化衍生物。
Org Lett. 2005 Mar 31;7(7):1375-8. doi: 10.1021/ol050188x.
6
Amphidinolide X, a novel 16-membered macrodiolide from dinoflagellate Amphidinium sp.安福菌素X，一种来自双鞭甲藻的新型16元大环二萜内酯。
J Org Chem. 2003 Jun 27;68(13):5339-45. doi: 10.1021/jo0343634.
7
Seaweed resistance to microbial attack: a targeted chemical defense against marine fungi.海藻对微生物攻击的抗性：针对海洋真菌的靶向化学防御。
Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6916-21. doi: 10.1073/pnas.1131855100. Epub 2003 May 19.
8
Novel actin depolymerizing macrolide aplyronine A.新型肌动蛋白解聚大环内酯类化合物阿普利罗宁A。
J Biochem. 1996 Sep;120(3):552-5. doi: 10.1093/oxfordjournals.jbchem.a021449.
9
Mycalolide B, a novel actin depolymerizing agent.肉珊瑚内酯B，一种新型的肌动蛋白解聚剂。
J Biol Chem. 1994 Nov 25;269(47):29710-4.
10
Tolytoxin and new scytophycins from three species of Scytonema.
J Nat Prod. 1990 Nov-Dec;53(6):1533-42. doi: 10.1021/np50072a021.
Zotero 插件