Charnock J S, Sundram K, Abeywardena M Y, McLennan P L, Tan D T
CSIRO, Division of Human Nutrition, O'Halloran Hill, South Australia.
Am J Clin Nutr. 1991 Apr;53(4 Suppl):1047S-1049S. doi: 10.1093/ajcn/53.4.1047S.
The effect of long-term feeding of various dietary fats and oils on cardiac arrhythmia was studied in an animal model of sudden cardiac death. After confirmation that a dietary supplement of saturated animal fat (SF) increased the animals' susceptibility to develop cardiac arrhythmia under ischemic stress whereas the polyunsaturated fatty acids of sunflower seed oil (SSO) reduced this susceptibility, we found that diets supplemented with either chemically refined palm oil (PO-I) or physically refined palm oil (PO-II) gave results that were generally intermediate in value between the SF and the SSO groups. However, during reperfusion of a previously ischemic heart, both PO-I- and PO-II-supplemented diets appeared to be as effective as SSO in reducing ventricular premature beats. In addition, the incidence of animals displaying severe ventricular fibrillation was much less after palm-oil feeding than it was after SF feeding. These preliminary results warrant further investigation of the potential antiarrhythmic effects of commercial palm oil.
在心脏性猝死动物模型中研究了长期喂食各种膳食脂肪和油类对心律失常的影响。在确认膳食补充饱和动物脂肪(SF)会增加动物在缺血应激下发生心律失常的易感性,而葵花籽油(SSO)的多不饱和脂肪酸可降低这种易感性之后,我们发现,补充化学精炼棕榈油(PO-I)或物理精炼棕榈油(PO-II)的饮食所产生的结果,其数值通常介于SF组和SSO组之间。然而,在先前缺血心脏的再灌注过程中,补充PO-I和PO-II的饮食在减少室性早搏方面似乎与SSO一样有效。此外,喂食棕榈油后出现严重心室颤动的动物发生率远低于喂食SF后。这些初步结果值得进一步研究市售棕榈油的潜在抗心律失常作用。