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[风湿病中的温泉疗法。基于法国国家卫生管理局和欧洲抗风湿病联盟临床指南的适应症,以及19项随机临床试验的结果]

[Spa therapy in rheumatology. Indications based on the clinical guidelines of the French National Authority for health and the European League Against Rheumatism, and the results of 19 randomized clinical trials].

作者信息

Françon Alain, Forestier Romain

机构信息

Centre de recherches rhumatologiques et thermales, 73100 Aix les Bains.

出版信息

Bull Acad Natl Med. 2009 Jun;193(6):1345-56; discussion 1356-8.

Abstract

UNLABELLED

The objective of this work was to update the rheumatologic indications of spa therapy, based on clinical practice guidelines published by the French National Authority for Health (HAS) and the European League Against Rheumatism (EULAR), and on the results of randomized clinical trials (RCT) METHODOLOGY: We first examined the indications for which spa therapy is mentioned and/or recommended in HAS and EULAR guidelines. We then identified RCTs in spa therapy and rheumatology by using the key words spa therapy, balneology, balneotherapy, hydrotherapy, mud therapy and mineral water in the Pubmed, Pascal and Embase databases. Only RCTs including a statistical analysis of between-group outcomes were retained We also examined the possible contribution of RCTs not listed in the bibliography of the guidelines.

RECOMMENDATIONS

spa therapy is recommended by HAS for chronic lower back pain, rank B and for stabilized rheumatoid arthritis, rank C. In ankylosing spondylitis, EULAR classifies spa therapy along with physiotherapy, rank A. In fibromyalgia, EULAR recommends hot-water balneology, an important component of spa therapy, rank B, based on five RCTs, of which three were carried out in thermal springs. Nineteen RCTs that comprised a statistical comparison of between-group outcomes were identified Sixteen studies indicated a persistent improvement (at least twelve weeks) in pain, analgesic and non-steroidal antiinflammatory drug consumption, functional capacity and/or quality of life, in the following indications: chronic lower back pain, knee osteoarthritis, hand osteoarthritis, fibromyalgia, ankylosing spondylitis andrheumatoidarthritis (PR).

CONCLUSION

Spa therapy, or hot-water balneology, appears to be indicated for chronic low back pain, stabilized rheumatoid arthritis, ankylosing spondylitis and fibromyalgia. RCT findings suggest that patients with knee and hand osteoarthritis might also benefit.

摘要

未标注

本研究的目的是根据法国国家卫生管理局(HAS)和欧洲抗风湿病联盟(EULAR)发布的临床实践指南以及随机临床试验(RCT)结果,更新水疗疗法的风湿病学适应症。

方法

我们首先研究了HAS和EULAR指南中提及和/或推荐水疗疗法的适应症。然后,我们通过在Pubmed、Pascal和Embase数据库中使用关键词“水疗疗法”“浴疗法”“浴疗”“水疗法”“泥疗法”和“矿泉水”来识别水疗疗法和风湿病学方面的随机对照试验。仅保留了包括组间结果统计分析的随机对照试验。我们还研究了指南参考文献中未列出的随机对照试验的可能贡献。

建议

HAS推荐水疗疗法用于慢性下腰痛(B级)和稳定期类风湿关节炎(C级)。在强直性脊柱炎方面,EULAR将水疗疗法与物理治疗归为一类(A级)。在纤维肌痛方面,基于五项随机对照试验(其中三项在温泉中进行),EULAR推荐热水浴疗法(水疗疗法的一个重要组成部分),为B级。共识别出19项包含组间结果统计比较的随机对照试验。16项研究表明,在以下适应症中,疼痛、镇痛药和非甾体抗炎药的使用、功能能力和/或生活质量持续改善(至少12周):慢性下腰痛、膝骨关节炎、手骨关节炎、纤维肌痛、强直性脊柱炎和类风湿关节炎(PR)。

结论

水疗疗法或热水浴疗法似乎适用于慢性下腰痛、稳定期类风湿关节炎、强直性脊柱炎和纤维肌痛。随机对照试验的结果表明,膝骨关节炎和手骨关节炎患者可能也会从中受益。

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