Silas O A, Echejoh G O, Manasseh A N, Mandong B M
Department of pathology, Jos University Teaching Hospital, Jos, Plateau State.
Niger J Med. 2009 Jul-Sep;18(3):282-5. doi: 10.4314/njm.v18i3.51182.
Salivary gland tumours are common head and neck tumours and more common in western world than Africans. Most salivary gland tumours are benign but the morbidity and mortality as expected is higher with malignant tumours. This study is aimed at describing the histological pattern, age, sex and site distribution of malignant salivary gland tumours in Jos University Teaching Hospital (JUTH) Jos from January 1998 to December 2007.
This is a descriptive study of all histologically confirmed malignant salivary gland tumours over a period of ten years. Fresh sections of tissue blocks of these lesions were made using the microtome (3 micrones). They were made into slides and stained with Hematoxylin and Eosin (H and E) and Periodic Acid Schiff (PAS) stains. The slides were reported independently by four pathologists. Diagnosis was made and classification done according to the World Health Organisation (WHO) classification of salivary gland tumours 3. Information such as age, sex and-site of distribution of these tumours was gotten from the patient's case files. The data was analyzed manually.
Muco-epidermoid carcinoma accounted for the highest (32 cases) histologic type. Malignant salivary gland tumours occurred more within the age range 40 to 69 years with the age group 50-59 years accounting for the highest frequency (36 cases). Most of these malignant salivary gland tumours occurred more in the parotid gland, the minor salivary being the least site of occurrence.
Mucoeperdermiod carcinoma is the commonest salivary gland tumour and that malignant salivary gland tumours in this study and it occurred more after the 5th decade of life.
涎腺肿瘤是常见的头颈部肿瘤，在西方世界比非洲更为常见。大多数涎腺肿瘤是良性的，但正如预期的那样，恶性肿瘤的发病率和死亡率更高。本研究旨在描述1998年1月至2007年12月在乔斯大学教学医院（JUTH）乔斯院区的恶性涎腺肿瘤的组织学模式、年龄、性别和部位分布。
这是一项对所有经组织学确诊的恶性涎腺肿瘤进行的为期十年的描述性研究。使用切片机（3微米）制作这些病变组织块的新鲜切片。将其制成载玻片，并用苏木精和伊红（H&E）以及过碘酸希夫（PAS）染色。四张载玻片由四位病理学家独立报告。根据世界卫生组织（WHO）涎腺肿瘤分类3进行诊断和分类。这些肿瘤的年龄、性别和分布部位等信息从患者病历中获取。数据进行手工分析。
黏液表皮样癌占组织学类型的比例最高（32例）。恶性涎腺肿瘤多发生在40至69岁年龄范围内，其中50 - 59岁年龄组的发病率最高（36例）。这些恶性涎腺肿瘤大多发生在腮腺，小涎腺是最少发生的部位。
黏液表皮样癌是最常见的涎腺肿瘤，本研究中的恶性涎腺肿瘤多发生在生命的第五个十年之后。
