Sotnikov S V, Stepaniuk V L, Umriukhin A E
Zh Vyssh Nerv Deiat Im I P Pavlova. 2009 Nov-Dec;59(6):736-42.
The influence of exposure to immobilization stress on TNF alpha and IL-4 concentrations in blood was studied in behaviorally active vs. passive in the open field Wistar rats. One hour after exposure to stress, blood concentrations of TNF alpha and IL-4 were significantly lower in behaviorally passive as compared to active rats and passive controls not exposed to stress. Moreover, in passive rats exposed to stress, the pituitary weight increased as compared to passive controls. Behaviorally passive rats exposed to emotional stress were characterized by a decreased blood levels of TNF alpha and IL-4 as compared to behaviorally passive controls and behaviorally active animals exposed to stress.
在旷场实验中，对行为活跃型与被动型的Wistar大鼠，研究了暴露于制动应激对血液中肿瘤坏死因子α（TNFα）和白细胞介素4（IL-4）浓度的影响。暴露于应激1小时后，与活跃大鼠及未暴露于应激的被动对照组相比，行为被动大鼠血液中TNFα和IL-4的浓度显著降低。此外，与被动对照组相比，暴露于应激的被动大鼠垂体重量增加。与行为被动对照组及暴露于应激的行为活跃动物相比，暴露于情绪应激的行为被动大鼠的特征是血液中TNFα和IL-4水平降低。
