[Influence of exposure to immobilisation stress on blood concentration of TNF alpha and IL-4 in rats active and passive in the open field test].

The influence of exposure to immobilization stress on TNF alpha and IL-4 concentrations in blood was studied in behaviorally active vs. passive in the open field Wistar rats. One hour after exposure to stress, blood concentrations of TNF alpha and IL-4 were significantly lower in behaviorally passive as compared to active rats and passive controls not exposed to stress. Moreover, in passive rats exposed to stress, the pituitary weight increased as compared to passive controls. Behaviorally passive rats exposed to emotional stress were characterized by a decreased blood levels of TNF alpha and IL-4 as compared to behaviorally passive controls and behaviorally active animals exposed to stress.