Ciok-Pater Emilia, Gospodarek Eugenia, Prazyńska Małgorzata, Bogiel Tomasz
Zakład Mikrobiologii Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikołaja Kopernika w Toruniu.
Med Dosw Mikrobiol. 2009;61(3):273-80.
The increase of fungal infections in recent years is connected with the progress in medicine. The vast usage of biomaterials is an inseparable element of contemporary medicine but it also leads to development of infections. The ability to produce biofilm by those yeasts plays an important role in the pathogenesis of candidiasis. Candida biofilm can form on the surface of plastic materials (silicon, polychloride vinyl, polymethacrylate methyl) used to catheters, drains and dentures production that is why it is a serious problem in case of fungal infections in patients who during the diagnosis and treatment have contact with biomaterials. The aim of the study was the assessment of ability to form biofilm on the surface of different biomaterials (latex silicon, polychloride vinyl, polystyrene, nylon and polymethacrylate methyl). 150 strains of Candida sp. were examined: 85 (56.7%) C. albicans and 65 (43.3%) C. non-albicans. The examined yeasts produced biofilm on the surface of polymethacrylate methyl in 39.3%, latex silicone in 38.7%, polychloride vinyl in 38.0%, polystyrene in 35.3% and nylon in 30.7%. Biofilm was most frequently produced by the strains of C. albicans, C. tropicalis, C. glabrata, C. parapsilosis, C. krusei and C. lusitaniae species.
近年来真菌感染的增加与医学进步相关。生物材料的广泛使用是当代医学不可或缺的要素，但它也会引发感染。这些酵母菌形成生物膜的能力在念珠菌病的发病机制中起着重要作用。念珠菌生物膜可在用于生产导管、引流管和假牙的塑料材料（硅、聚氯乙烯、聚甲基丙烯酸甲酯）表面形成，这就是为什么对于在诊断和治疗过程中接触生物材料的患者而言，真菌感染是一个严重问题。本研究的目的是评估不同生物材料（乳胶硅、聚氯乙烯、聚苯乙烯、尼龙和聚甲基丙烯酸甲酯）表面形成生物膜的能力。检测了150株念珠菌属菌株：85株（56.7%）白色念珠菌和65株（43.3%）非白色念珠菌。所检测的酵母菌在聚甲基丙烯酸甲酯表面形成生物膜的比例为39.3%，在乳胶硅表面为38.7%，在聚氯乙烯表面为38.0%，在聚苯乙烯表面为35.3%，在尼龙表面为30.7%。生物膜最常由白色念珠菌、热带念珠菌、光滑念珠菌、近平滑念珠菌、克柔念珠菌和葡萄牙念珠菌菌株产生。
