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定义脊髓肿瘤研究的未来方向:来自美国国立卫生研究院研讨会的会议记录。

Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop.

机构信息

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA.

出版信息

J Neurosurg Spine. 2010 Feb;12(2):117-21. doi: 10.3171/2009.7.SPINE09137.

Abstract

The relative rarity of spinal cord tumors has hampered the study of these uncommon nervous system malignancies. Consequently, the understanding of the fundamental biology and optimal treatment of spinal cord tumors is limited, and these cancers continue to inflict considerable morbidity and mortality in children and adults. As a first step to improving the outcome of patients affected with spinal cord tumors, the National Institutes of Health Office of Rare Diseases Research in cooperation with the National Cancer Institute and the National Institute of Neurological Disorders and Stroke convened a workshop to discuss the current status of research and clinical management of these tumors. The overall goal of this meeting was to initiate a process that would eventually translate fundamental basic science research into improved clinical care for this group of patients. Investigational priorities for each of these areas were established, and the opportunities for future multidisciplinary research collaborations were identified.

摘要

脊髓肿瘤相对少见,这给这些罕见的神经系统恶性肿瘤的研究带来了困难。因此,人们对脊髓肿瘤的基础生物学和最佳治疗方法的了解有限,这些癌症仍在儿童和成人中造成相当大的发病率和死亡率。为了提高脊髓肿瘤患者的治疗效果,美国国立卫生研究院罕见疾病研究办公室与美国国家癌症研究所、美国国立神经病学与卒中研究所合作,召开了一次研讨会,讨论这些肿瘤的研究和临床管理现状。本次会议的总体目标是启动一个过程,最终将基础科学研究转化为这组患者的临床治疗。为每个领域都制定了研究重点,并确定了未来多学科研究合作的机会。

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