Department of Rehabilitation Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA.
Shepherd Center, Atlanta, Georgia, USA.
J Neurotrauma. 2021 May 1;38(9):1251-1266. doi: 10.1089/neu.2020.7174. Epub 2021 Feb 3.
The spinal cord injury (SCI) research community has experienced great advances in discovery research, technology development, and promising clinical interventions in the past decade. To build upon these advances and maximize the benefit to persons with SCI, the National Institutes of Health (NIH) hosted a conference February 12-13, 2019 titled "SCI 2020: Launching a Decade of Disruption in Spinal Cord Injury Research." The purpose of the conference was to bring together a broad range of stakeholders, including researchers, clinicians and healthcare professionals, persons with SCI, industry partners, regulators, and funding agency representatives to break down existing communication silos. Invited speakers were asked to summarize the state of the science, assess areas of technological and community readiness, and build collaborations that could change the trajectory of research and clinical options for people with SCI. In this report, we summarize the state of the science in each of five key domains and identify the gaps in the scientific literature that need to be addressed to move the field forward.
在过去的十年中,脊髓损伤(SCI)研究领域在发现研究、技术发展和有前途的临床干预方面取得了重大进展。为了在这些进展的基础上更进一步,使脊髓损伤患者最大程度受益,美国国立卫生研究院(NIH)于 2019 年 2 月 12 日至 13 日举办了一场题为“SCI 2020:开启脊髓损伤研究颠覆的十年”的会议。会议的目的是召集广泛的利益相关者,包括研究人员、临床医生和医疗保健专业人员、脊髓损伤患者、行业合作伙伴、监管机构和资助机构代表,打破现有的沟通隔阂。受邀演讲者被要求总结科学现状,评估技术和社区准备情况,并建立可能改变研究轨迹和脊髓损伤患者临床选择的合作关系。在本报告中,我们总结了五个关键领域的科学现状,并确定了需要解决的科学文献中的差距,以推动该领域的发展。