解释性与实用主义基于试验的经济评估：在烧伤替代疗法中的应用。

Explanatory versus pragmatic trial-based economic evaluations: application to alternative therapies for burns.

机构信息

Department of Public Health, Faculty of Health and Caring Professions, Technological Educational Institute of Athens, Athens, Greece.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2010 Feb;10(1):37-48. doi: 10.1586/erp.09.75.

DOI:10.1586/erp.09.75

Abstract

The debate concerning the adoption of a pragmatic or explanatory attitude to clinical trials as well as the exact points of distinction between the two attitudes, has lasted for more than 40 years. Recently, new methodological proposals have been given as a pragmatic-explanatory continuum indicator summary tool and mechanistic-practical framework to distinguish the two attitudes. In this review, we provide a guide to the literature concerning the debate regarding the choice between explanatory and pragmatic attitudes in trial-based economic evaluations, focusing on the therapies for burns.

摘要

关于对临床试验采取务实还是解释的态度的争论，以及这两种态度的确切区别，已经持续了 40 多年。最近，有人提出了新的方法学建议，作为一种实用-解释连续体指标综合工具和机械-实用框架，以区分这两种态度。在这篇综述中，我们提供了一个关于基于试验的经济评估中解释性和务实性态度选择的文献指南，重点关注烧伤治疗的疗法。

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引用本文的文献

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Poor reporting quality and high proportion of missing data in economic evaluations alongside pragmatic trials: a cross-sectional survey.实用试验中经济评估的报告质量差及数据缺失比例高：一项横断面调查

BMC Med Res Methodol. 2025 Mar 6;25(1):61. doi: 10.1186/s12874-025-02519-z.

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Comparing oil based ointment versus standard practice for the treatment of moderate burns in Greece: a trial based cost effectiveness evaluation.比较油基软膏与希腊标准治疗中度烧伤的效果：一项基于试验的成本效益评估。

BMC Complement Altern Med. 2011 Dec 1;11:122. doi: 10.1186/1472-6882-11-122.

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