Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.
Am J Transplant. 2010 Mar;10(3):464-71. doi: 10.1111/j.1600-6143.2009.02987.x. Epub 2010 Jan 29.
The 10th Banff Conference on Allograft Pathology was held in Banff, Canada from August 9 to 14, 2009. A total of 263 transplant clinicians, pathologists, surgeons, immunologists and researchers discussed several aspects of solid organ transplants with a special focus on antibody mediated graft injury. The willingness of the Banff process to adapt continuously in response to new research and improve potential weaknesses, led to the implementation of six working groups on the following areas: isolated v-lesion, fibrosis scoring, glomerular lesions, molecular pathology, polyomavirus nephropathy and quality assurance. Banff working groups will conduct multicenter trials to evaluate the clinical relevance, practical feasibility and reproducibility of potential changes to the Banff classification. There were also sessions on quality improvement in biopsy reading and utilization of virtual microscopy for maintaining competence in transplant biopsy interpretation. In addition, compelling molecular research data led to the discussion of incorporation of omics-technologies and discovery of new tissue markers with the goal of combining histopathology and molecular parameters within the Banff working classification in the near future.
2009 年 8 月 9 日至 14 日，第 10 届 Banff 同种异体移植病理学大会在加拿大班夫举行。共有 263 名移植临床医生、病理学家、外科医生、免疫学家和研究人员参加了会议，重点讨论了实体器官移植的几个方面，特别是抗体介导的移植物损伤。Banff 会议进程愿意不断适应新的研究并改进潜在的弱点，因此成立了六个工作组，分别负责以下领域：孤立的血管病变、纤维化评分、肾小球病变、分子病理学、多瘤病毒肾病和质量保证。Banff 工作组将进行多中心试验，以评估 Banff 分类潜在变化的临床相关性、实际可行性和可重复性。会议还包括关于活检解读质量改进和虚拟显微镜在保持移植活检解读能力方面的应用，以评估 Banff 分类潜在变化的临床相关性、实际可行性和可重复性。此外，引人注目的分子研究数据促使人们讨论将组学技术和新的组织标志物纳入其中，以期在不久的将来将组织病理学和分子参数结合到 Banff 工作组分类中。
