INSERM, UMR-S 707, Paris.
Clin Microbiol Infect. 2010 Apr;16(4):393-6. doi: 10.1111/j.1469-0691.2010.03166.x. Epub 2010 Jan 27.
The clinical burden of the A/H1NI influenza pandemic in the general population is comparable to those of previous seasonal influenza epidemics in terms of total numbers of clinical cases. It is higher in young, and virtually nil in older adults. These assertions can be made safely because of long-established clinical influenza surveillance systems. However, what characterizes this pandemic is that it may kill young patients without known risk factors. Surveillance systems dedicated to the most severely ill patients admitted to intensive care units have been implemented only recently. The present experience strongly supports the view that they should be made perennial.
从临床病例总数来看，甲型 H1N1 流感大流行给普通人群带来的临床负担与以往季节性流感流行相当。在年轻人中负担较高，而在老年人中几乎为零。这些结论是基于长期建立的临床流感监测系统得出的，是安全可靠的。然而，此次大流行的特点是，它可能会导致没有已知危险因素的年轻患者死亡。最近才开始建立专门针对入住重症监护病房的最严重患者的监测系统。目前的经验强烈支持应将这些系统作为常年监测的观点。
