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告别洋地黄?洋地黄类药物使用减少。

A fond farewell to the foxglove? The decline in the use of digitalis.

机构信息

UMDNJ - New Jersey Medical School, Springfield, NJ 07081, USA.

出版信息

J Card Fail. 2010 Jan;16(1):45-8. doi: 10.1016/j.cardfail.2009.08.001. Epub 2009 Sep 3.

Abstract

Since William Withering's report on the foxglove in 1785, digitalis, in 1 form or another, has remained a mainstay in the treatment of congestive heart failure and as a means of rate control in atrial fibrillation. Recently, with the introduction of potent diuretics and other agents for the treatment of these conditions, there has been a deemphasis on the role of digitalis despite its therapeutic value. Continued evidence of the frequent usefulness of digitalis in both conditions suggests that this venerable drug should remain within the therapeutic armamentarium of cardiologists and other physicians.

摘要

自 1785 年威廉·威瑟林(William Withering)报告洋地黄以来,洋地黄制剂一直以某种形式作为充血性心力衰竭治疗的主要药物,并作为控制心房颤动时心室率的手段。最近,随着强效利尿剂和其他治疗这些疾病的药物的出现,尽管洋地黄具有治疗价值,但人们对其作用的重视程度有所降低。洋地黄在这两种疾病中频繁应用的证据持续表明,这种古老的药物应继续保留在心脏病专家和其他医生的治疗武器库中。

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