SUNY Upstate Medical University, Department of Psychiatry and Behavioral Sciences, 750 East Adams Street, Syracuse, NY 13210, USA.
Mol Genet Metab. 2010;99 Suppl 1:S52-8. doi: 10.1016/j.ymgme.2009.09.013.
Despite having average intellectual abilities, academic difficulties are relatively common in children and adolescents with PKU. These academic difficulties may be a function of attention deficit hyperactivity disorder (ADHD), executive functioning deficits, and processing speed deficits, all of which are known to affect academic performance in non-PKU populations. This review focuses on what is currently known about academic performance in youth with PKU and offers suggestions for future research.
尽管平均智力水平正常，但 PKU 患儿和青少年仍普遍存在学习困难的问题。这些学习困难可能与注意力缺陷多动障碍（ADHD）、执行功能缺陷和处理速度缺陷有关，这些因素在非 PKU 人群中均已知会影响学习成绩。本综述重点介绍了目前已知的关于 PKU 青少年学习成绩的信息，并为未来的研究提供了建议。
