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基层医疗中精神障碍的阳性筛查:未治疗患者的长期随访。

Positive screens for psychiatric disorders in primary care: a long-term follow-up of patients who were not in treatment.

机构信息

Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

出版信息

Psychiatr Serv. 2010 Feb;61(2):151-9. doi: 10.1176/ps.2010.61.2.151.

Abstract

OBJECTIVE

Screening for psychiatric disorders has gained acceptance in some general medical settings, but critics argue about its value. The purpose of this study was to determine the clinical utility of screening by conducting a long-term follow-up of patients who screened positive for psychiatric disorders but who were initially not in treatment.

METHODS

A cohort of 519 low-income, adult primary care patients were screened for major depression and bipolar, anxiety, and substance use disorders and reassessed with the Structured Clinical Interview for DSM-IV after a mean of 3.7 years by a clinician blind to the initial screen. Data on treatment utilization was obtained through hospital records. The sample consisted of 348 patients who had not received psychiatric care in the year before screening.

RESULTS

Among 39 patients who screened positive for major depression, 62% (95% confidence interval=45.5%-77.6%) met criteria for current major depressive disorder at follow-up. Those who screened positive reported significantly poorer mental and social functioning and worse general health at follow-up than the screen-negative patients and were more likely to have visited the emergency department for psychiatric reasons (12.1% and 3.0%, odds ratio [OR]=6.4) and to have major depression (OR=7.6). Generally similar results were observed for patients who screened positive for other disorders.

CONCLUSIONS

Commonly used screening methods identified patients with psychiatric disorders; about four years later, those not initially in treatment were likely to have enduring symptoms and to use emergency psychiatric services. Screening should be followed up by clinical diagnostic assessment in the context of available mental health treatment.

摘要

目的

在一些普通医疗环境中,精神障碍筛查已经得到认可,但批评者对其价值存在争议。本研究的目的是通过对最初未接受治疗的筛查阳性精神障碍患者进行长期随访,确定筛查的临床实用性。

方法

对 519 名低收入成年初级保健患者进行了主要抑郁症、双相情感障碍、焦虑症和物质使用障碍的筛查,并在平均 3.7 年后由一名对初始筛查不知情的临床医生使用 DSM-IV 结构临床访谈进行了重新评估。通过医院记录获得了治疗利用数据。样本由 348 名在筛查前一年未接受精神科治疗的患者组成。

结果

在 39 名筛查出患有重度抑郁症的患者中,有 62%(95%置信区间=45.5%-77.6%)在随访时符合当前重度抑郁症的标准。筛查阳性的患者报告说,与筛查阴性的患者相比,他们的心理健康和社会功能明显较差,一般健康状况也较差,因精神原因就诊于急诊室的可能性更高(12.1%和 3.0%,比值比[OR]=6.4),患有重度抑郁症的可能性也更高(OR=7.6)。对于筛查出其他障碍的患者,也观察到了大致相似的结果。

结论

常用的筛查方法识别出了患有精神障碍的患者;大约四年后,那些最初未接受治疗的患者可能会持续出现症状,并使用急诊精神科服务。在提供心理健康治疗的背景下,应在临床诊断评估后进行筛查。

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