两种自动化免疫分析系统在检测同时存在抗原和抗体的血清样本中乙肝病毒标志物时的差异。
Discrepancies between two automated immunoassay systems in determining hepatitis B virus markers in serum samples with concomitant presence of antigens and antibodies.
作者信息
Cheng Liming, Guan Qing, Zhang Junxia, Sun Ziyong
机构信息
Department of Laboratory Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
出版信息
Ann Clin Lab Sci. 2010 Winter;40(1):49-52.
This study compared the assay results of HBV markers obtained with two automated immunoassay systems in serum samples with concomitant HBV antigens and antibodies. Eighty-nine samples of concomitant HBsAg and anti-HBs and 74 samples of concomitant HBeAg and anti-HBe were analyzed by the Abbott Architect i2000 and the Roche Elecsys 2010 immunoassay systems. The overall concordance rates of the Architect and Elecsys results were 78.6% for samples with concomitant HBsAg and anti-HBs and 77% for samples with concomitant HBeAg and anti-HBe. The data show that substantial differences exist between the results obtained by these two systems, especially in determining anti-HBs and HBeAg at low concentrations.
本研究比较了两种自动免疫分析系统在含有乙肝病毒（HBV）抗原和抗体的血清样本中检测HBV标志物的检测结果。采用雅培Architect i2000和罗氏Elecsys 2010免疫分析系统，对89份同时含有HBsAg和抗-HBs的样本以及74份同时含有HBeAg和抗-HBe的样本进行了分析。对于同时含有HBsAg和抗-HBs的样本，Architect和Elecsys结果的总体一致性率为78.6%；对于同时含有HBeAg和抗-HBe的样本，一致性率为77%。数据表明，这两种系统所获结果存在显著差异，尤其是在低浓度抗-HBs和HBeAg的测定方面。
Zotero 插件