Department of Psychology, University of California, San Diego, 9500 Gilman Drive, Mail Code 0804, La Jolla, CA 92093-0804, USA.
Psychosom Med. 2010 Apr;72(3):266-72. doi: 10.1097/PSY.0b013e3181d0d8b2. Epub 2010 Feb 2.
To investigate whether an association exists between experiences of everyday discrimination and blood pressure (BP) dipping in a biracial sample of black and white adults. Attenuated nocturnal BP dipping is closely linked to cardiovascular morbidity and mortality. Self-reported experiences of everyday discrimination have also been associated with negative cardiovascular health outcomes.
Seventy-eight hypertensive and normotensive women and men (n = 30 black and 48 white) reported on their experiences of everyday discrimination (Everyday Discrimination Scale) and underwent two separate 24-hour ambulatory BP monitoring (ABPM) sessions approximately 1 week apart.
Correlation analysis revealed that higher endorsement of everyday discrimination was significantly associated with less diastolic BP (DBP) and systolic BP (SBP) dipping (p < .05). Subsequent hierarchical regression analyses indicated that everyday discrimination explained 8% to 11% of the variance in SBP and DBP dipping above and beyond other demographic and life-style-related factors, including race, age, 24-hour BP, body mass index, and current socioeconomic status. The relationship between discrimination and dipping was significantly stronger on the second night of monitoring. Finally, analyses revealed that everyday discrimination mediated the relationship between race and BP dipping.
These findings suggest that experiences of everyday discrimination are associated with less nocturnal SBP and DBP dipping above and beyond the effect of known covariates. The use of multiple ABPM sessions may facilitate the detection of relationships between psychological variables and BP dipping.
探究在黑人和白人的混合样本中,日常歧视经历与血压(BP)昼夜节律变化之间是否存在关联。夜间 BP 下降减弱与心血管发病率和死亡率密切相关。自我报告的日常歧视经历也与心血管健康不良结局有关。
78 名高血压和正常血压的女性和男性(n=30 名黑人,48 名白人)报告了他们的日常歧视经历(日常歧视量表),并在大约 1 周的时间内进行了两次单独的 24 小时动态血压监测(ABPM)。
相关分析显示,日常歧视的认同度越高,舒张压(DBP)和收缩压(SBP)昼夜节律变化越小(p<0.05)。随后的分层回归分析表明,日常歧视解释了 SBP 和 DBP 昼夜节律变化的 8%至 11%的方差,超出了种族、年龄、24 小时 BP、体重指数和当前社会经济地位等其他人口统计学和生活方式相关因素。在第二次监测夜间,歧视与昼夜节律变化之间的关系明显更强。最后,分析表明,日常歧视在种族和 BP 昼夜节律变化之间起中介作用。
这些发现表明,日常歧视经历与夜间 SBP 和 DBP 昼夜节律变化减弱有关,这超出了已知协变量的影响。使用多个 ABPM 监测可以促进检测心理变量与 BP 昼夜节律变化之间的关系。