Center for Minimal-Invasive Surgery, Department of General and Bariatric Surgery, Krankenhaus Sachsenhausen, Frankfurt/M., Germany.
Obes Facts. 2009;2 Suppl 1(Suppl 1):20-3. doi: 10.1159/000198243. Epub 2009 Mar 18.
Gastric balloon therapy (GBT) is a temporary, nonsurgical treatment for obesity. This retrospective study evaluates safety and efficacy of GBT in obese patients.
The BioEnterics. Intragastric Balloon (BIB) was endoscopically implanted into each patient's stomach and inflated with saline (450-750 ml). Extraction was planned after 6 months. Data from 190 patients receiving GBT were evaluated. Mean weight was 168.4 +/- 58.9 kg (range 76.5-310.0) and mean BMI was 55.6 +/- 17.5 kg/m2 (range 27.0-95.7).
Mean weight loss at the time of balloon removal was 21.2 +/- 14.0 kg (range 0-80.0). The mean BMI loss and EBL(Excess BMI Loss) were 7.2 +/- 4.9 kg/m2 (range 0-28.9) and 30.1 +/- 26.4% (0-184.4), respectively. The most substantial weight and BMI loss was observed in the most massively obese patients. Minor complications at implantation were encountered in 2 cases (1.1%) due to leakage of the balloon, and in 3 cases at explantation (1.6%). No mortality or major complications such as gastric perforation or ulcers occurred. Of the 190 patients, 76 received subsequent surgery (40.0%). Of those, 7 patients had a BMI < 50 kg/m2 while all other patients where super-obese (BMI > 50 kg/m2). 58 patients (30.5%) with a BMI > 60 kg/m2 which had an extraordinary high operation risk were able to receive subsequent surgical treatment because of a substantial weight loss and/or reduced comorbidity.
GBT appears to be a safe, tolerable, and potentially effective procedure for the initial treatment of morbid obesity.
胃气球治疗（GBT）是一种肥胖症的临时、非手术治疗方法。本回顾性研究评估了 GBT 在肥胖患者中的安全性和疗效。
将 BioEnterics. 胃内气球（BIB）经内镜植入每位患者的胃中，并注入生理盐水（450-750 毫升）。计划在 6 个月后取出。对 190 名接受 GBT 的患者的数据进行了评估。平均体重为 168.4 +/- 58.9 公斤（范围 76.5-310.0），平均 BMI 为 55.6 +/- 17.5 kg/m2（范围 27.0-95.7）。
在气球取出时的平均体重减轻量为 21.2 +/- 14.0 公斤（范围 0-80.0）。平均 BMI 减轻量和 EBL（超重 BMI 减轻量）分别为 7.2 +/- 4.9 kg/m2（范围 0-28.9）和 30.1 +/- 26.4%（0-184.4）。最肥胖的患者体重和 BMI 减轻量最大。在植入时，有 2 例（1.1%）因气球漏出而出现轻微并发症，在取出时，有 3 例（1.6%）出现并发症。无死亡或重大并发症，如胃穿孔或溃疡。190 名患者中，76 名患者接受了后续手术（40.0%）。其中，7 名患者 BMI<50kg/m2，而所有其他患者均为超级肥胖（BMI>50kg/m2）。58 名 BMI>60kg/m2 的患者（30.5%）由于体重显著减轻和/或合并症减少，能够接受后续手术治疗，手术风险极高。
GBT 似乎是一种安全、耐受和潜在有效的肥胖症初始治疗方法。
