Department of Food and Nutrition, Research Institute of Human Ecology Seoul National University, Seoul 151-742, Korea.
Nutr Res Pract. 2008 Spring;2(1):3-7. doi: 10.4162/nrp.2008.2.1.3. Epub 2008 Mar 31.
This study was carried out to investigate the efficacy of sn-2 palmitic acid-fortified vegetable oil (Sn2PA) on calcium absorption and to confirm the synergistic effects of fructooligosaccharide on calcium absorption. Male SD rats were fed 6 kinds of casein based diets containing vegetable oil (control), sn-2 palmitic acid-fortified vegetable oil (Sn2PA) and Sn2PA with fructooligosaccharide(Sn2PAFO) in two levels of calcium (normal 0.5% and high 1.0%) for 3 weeks. Total lipids, cholesterol, triglyceride and calcium in blood were measured. Feces were collected using cages for 4 days. Serum concentrations of total lipids and calcium were not significantly different among groups. However, serum triglyceride was significantly decreased by fructooligosaccharide supplementation regardless of dietary calcium level. The lipid absorption was not significantly different among experimental groups. Calcium absorption was significantly higher in Sn2PAFO group than other groups. Calcium solubility of intestine was increased by sn-2 palmitic acid supplementation. These results suggest that sn-2 palmitic acid and fructooligosaccharide supplementation could be beneficial for baby foods including infant formula, with regard to increasing absorption of calcium by more soluble calcium in the small intestinal content.
本研究旨在探讨富含 sn-2 棕榈酸的植物油 (Sn2PA) 对钙吸收的功效，并证实低聚果糖对钙吸收的协同作用。雄性 SD 大鼠分别喂食 6 种基于酪蛋白的日粮，日粮中含有植物油（对照）、富含 sn-2 棕榈酸的植物油 (Sn2PA) 和含 sn-2 棕榈酸和低聚果糖的植物油 (Sn2PAFO)，并分为高钙 (正常 0.5%和高钙 1.0%) 和低钙 (正常 0.5%和低钙 0.3%) 两种水平，共喂养 3 周。测定血液中的总脂、胆固醇、甘油三酯和钙。使用笼收集粪便 4 天。各组血清总脂和钙浓度无显著差异。然而，无论钙水平如何，低聚果糖的添加均可显著降低血清甘油三酯。实验组的脂质吸收无显著差异。Sn2PAFO 组的钙吸收显著高于其他组。sn-2 棕榈酸的添加增加了肠道钙的溶解度。这些结果表明，sn-2 棕榈酸和低聚果糖的添加可能有利于婴儿食品，包括婴儿配方奶粉，可增加肠道内容物中更易溶解的钙的吸收。
