Moreira Rodrigo O, Amâncio Ana Paula R L, Brum Hugo R, Vasconcelos Diane L, Nascimento Gilvan F
Faculdade de Medicina, Universidade Presidente Antônio Carlos, Juiz de Fora, MG, Brasil.
Arq Bras Endocrinol Metabol. 2009 Dec;53(9):1103-11. doi: 10.1590/s0004-27302009000900007.
To investigate the impact of depressive symptoms and neuropathic pain in the quality of life (QL) of diabetic patients with diabetic distal polyneuropathy (DDP).
Two hundred and four patients with type 2 diabetes mellitus were evaluated. The diagnosis of DDP was achieved using the Neuropathy Disability Score and Neuropathy Symptom Score questionnaires. The severity of neuropathic pain was assessed by means of a Visual Analogue Scale (VAS); the severity of depression, by means of the Beck Depression Inventory (BDI); and QL was assessed by means of the World Health Organization Quality of Life Instrument-bref (WHOQOLbref).
Patients with DDP presented significant higher scores in BDI (12.6 +/- 7.2 versus 9.9 +/- 7.3; p = 0.018) and in VAS (5.0 +/- 2.4 versus 2.6 +/- 2.9; p < 0.001). They also presented significant lower scores in the physical (52.8 +/- 15.5 versus 59.2 +/- 17.0; p = 0.027) and environmental domains (56.6 +/- 12.3 versus 59.6 +/- 13.6; p = 0,045).
Diabetic patients with DDP presented a worse QL in the physical and environmental domains of the WHOQOL-bref, probably due to more depressive symptoms and the severity of pain.
探讨抑郁症状和神经性疼痛对糖尿病远端多发性神经病变（DDP）糖尿病患者生活质量（QL）的影响。
对204例2型糖尿病患者进行评估。采用神经病变残疾评分和神经病变症状评分问卷对DDP进行诊断。通过视觉模拟量表（VAS）评估神经性疼痛的严重程度；通过贝克抑郁量表（BDI）评估抑郁的严重程度；通过世界卫生组织生活质量简表（WHOQOLbref）评估生活质量。
DDP患者的BDI评分（12.6±7.2对9.9±7.3；p = 0.018）和VAS评分（5.0±2.4对2.6±2.9；p < 0.001）显著更高。他们在生理领域（52.8±15.5对59.2±17.0；p = 0.027）和环境领域（56.6±12.3对59.6±13.6；p = 0.045）的得分也显著更低。
患有DDP的糖尿病患者在WHOQOL-bref的生理和环境领域生活质量较差，可能是由于更多的抑郁症状和疼痛的严重程度。
