2型糖尿病合并糖尿病远端多发性神经病变患者的抑郁症状与生活质量
[Depressive symptoms and quality of life in type 2 diabetic patients with diabetic distal polyneuropathy].
作者信息
Moreira Rodrigo O, Amâncio Ana Paula R L, Brum Hugo R, Vasconcelos Diane L, Nascimento Gilvan F
机构信息
Faculdade de Medicina, Universidade Presidente Antônio Carlos, Juiz de Fora, MG, Brasil.
出版信息
Arq Bras Endocrinol Metabol. 2009 Dec;53(9):1103-11. doi: 10.1590/s0004-27302009000900007.
OBJECTIVE
To investigate the impact of depressive symptoms and neuropathic pain in the quality of life (QL) of diabetic patients with diabetic distal polyneuropathy (DDP).
METHODS
Two hundred and four patients with type 2 diabetes mellitus were evaluated. The diagnosis of DDP was achieved using the Neuropathy Disability Score and Neuropathy Symptom Score questionnaires. The severity of neuropathic pain was assessed by means of a Visual Analogue Scale (VAS); the severity of depression, by means of the Beck Depression Inventory (BDI); and QL was assessed by means of the World Health Organization Quality of Life Instrument-bref (WHOQOLbref).
RESULTS
Patients with DDP presented significant higher scores in BDI (12.6 +/- 7.2 versus 9.9 +/- 7.3; p = 0.018) and in VAS (5.0 +/- 2.4 versus 2.6 +/- 2.9; p < 0.001). They also presented significant lower scores in the physical (52.8 +/- 15.5 versus 59.2 +/- 17.0; p = 0.027) and environmental domains (56.6 +/- 12.3 versus 59.6 +/- 13.6; p = 0,045).
CONCLUSIONS
Diabetic patients with DDP presented a worse QL in the physical and environmental domains of the WHOQOL-bref, probably due to more depressive symptoms and the severity of pain.
目的
探讨抑郁症状和神经性疼痛对糖尿病远端多发性神经病变（DDP）糖尿病患者生活质量（QL）的影响。
方法
对204例2型糖尿病患者进行评估。采用神经病变残疾评分和神经病变症状评分问卷对DDP进行诊断。通过视觉模拟量表（VAS）评估神经性疼痛的严重程度；通过贝克抑郁量表（BDI）评估抑郁的严重程度；通过世界卫生组织生活质量简表（WHOQOLbref）评估生活质量。
结果
DDP患者的BDI评分（12.6±7.2对9.9±7.3；p = 0.018）和VAS评分（5.0±2.4对2.6±2.9；p < 0.001）显著更高。他们在生理领域（52.8±15.5对59.2±17.0；p = 0.027）和环境领域（56.6±12.3对59.6±13.6；p = 0.045）的得分也显著更低。
结论
患有DDP的糖尿病患者在WHOQOL-bref的生理和环境领域生活质量较差，可能是由于更多的抑郁症状和疼痛的严重程度。
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