抑郁症与焦虑症的共病：与1型和2型糖尿病患者生活质量差的关联。
Comorbidity of depression and anxiety: association with poor quality of life in type 1 and 2 diabetic patients.
作者信息
de Ornelas Maia Ana Claudia C, Braga Arthur de Azevedo, Paes Flávia, Machado Sergio, Carta Mauro Giovanni, Nardi Antonio Egidio, Silva Adriana Cardoso
机构信息
Laboratory of Panic and Respiration -Institute of Psychiatry of Federal University of Rio de Janeiro, Rio de Janeiro - Brazil, National Institute of Translational Medicine (INCT-TM), Brazil.
出版信息
Clin Pract Epidemiol Ment Health. 2013 Jul 12;9:136-41. doi: 10.2174/1745017901309010136. Print 2013.
BACKGROUND
Diabetes is associates with depression and impairment in Quality of Life (QoL).
OBJECTIVE
The objective is to define the frequencies of depressive and anxiety symptoms in a sample of patients diagnosed with type 1 and 2 diabetes, the amount of impairment of QoL and the weight of depression and anxiety in determining the QoL in such of patients.
METHODS
A total of 210 patients were divided into two groups (type 1 and type 2). Patients completed the HADS and WHOQoL-bref.
RESULTS
Groups showed a high prevalence of anxiety (type 1 = 60%, type 2 = 43.8%) and depression (type 1 = 52.4%, type 2 = 38.1%), both measures were significantly higher (p < 0.05) in diabetes type 1 patients. Type 1 patients also showed a QoL in the overall assessment and the physical, psychological and social relations domains. In both Type 1 and 2 diabetes poor QoL was found associated by anxiety and depression comorbidity.
CONCLUSION
In overall diabetes patients depression and anxiety seems to be a determinant of poor QoL.
背景
糖尿病与抑郁症及生活质量（QoL）受损相关。
目的
确定1型和2型糖尿病确诊患者样本中抑郁和焦虑症状的发生率、生活质量受损程度，以及抑郁和焦虑在这类患者生活质量决定因素中的权重。
方法
总共210名患者被分为两组（1型和2型）。患者完成了医院焦虑抑郁量表（HADS）和世界卫生组织生活质量简表（WHOQoL-bref）。
结果
两组患者焦虑（1型 = 60%，2型 = 43.8%）和抑郁（1型 = 52.4%，2型 = 38.1%）的患病率都很高，1型糖尿病患者这两项指标均显著更高（p < 0.05）。1型患者在总体评估以及身体、心理和社会关系领域的生活质量也较低。在1型和2型糖尿病中，生活质量差均与焦虑和抑郁共病相关。
结论
总体而言，糖尿病患者的抑郁和焦虑似乎是生活质量差的决定因素。
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