Kehler M, Albrechtsson U, Andrésdóttir A, Brådvik I, Hochbergs P, Lárusdóttir H, Lundin A
Department of Diagnostic Radiology, University Hospital, Lund, Sweden.
Acta Radiol. 1991 Jan;32(1):18-23.
The subtle changes often found in interstitial lung disease can be difficult to evaluate at conventional radiography. In order to define the information obtained with digital radiography, it is particularly important to find out to what extent interstitial lung disease can be observed with this technique. Ninety-one patients, 56 with interstitial lung disease and 35 with normal lungs, were examined both with a digital system and with conventional film-screen technique. The examinations were reviewed independently by 4 radiologists with different experience and receiver operating characteristics (ROC) curves were constructed. The 2 systems were equal in diagnostic performance with no statistic difference between the conventional radiographs, the 2 digital images reviewed together or the 2 digital images reviewed separately. There was a significant difference between the 2 observers with the highest and the one with the lowest score only in the review of digital unsharp mask images, but otherwise no differences statistically. A lower number of false negatives and a higher number of false positives were seen with the digital unsharp mask image, producing a higher sensitivity and lower specificity.
间质性肺疾病中常发现的细微变化在传统放射成像中可能难以评估。为了明确数字放射成像所获得的信息，弄清楚利用该技术能够在何种程度上观察到间质性肺疾病尤为重要。91名患者接受了数字系统和传统屏-片技术检查，其中56例患有间质性肺疾病，35例肺部正常。4位经验不同的放射科医生独立复查这些检查结果，并构建了受试者操作特征（ROC）曲线。两种系统的诊断性能相当，传统X线片、一起复查的两张数字图像或分别复查的两张数字图像之间无统计学差异。仅在复查数字锐化掩模图像时，得分最高和最低的两位观察者之间存在显著差异，其他方面无统计学差异。数字锐化掩模图像出现的假阴性数量较少，假阳性数量较多，从而产生较高的敏感性和较低的特异性。
