Department of Psychology, Tel Aviv University, Tel Aviv, Israel.
Hum Brain Mapp. 2010 Oct;31(10):1490-501. doi: 10.1002/hbm.20952.
A face-selective neural signal is reliably found in humans with functional MRI and event-related potential (ERP) measures, which provide complementary information about the spatial and temporal properties of the neural response. However, because most neuroimaging studies so far have studied ERP and fMRI face-selective markers separately, the relationship between them is still unknown. Here we simultaneously recorded fMRI and ERP responses to faces and chairs to examine the correlations across subjects between the magnitudes of fMRI and ERP face-selectivity measures. Findings show that the face-selective responses in the temporal lobe (i.e., fusiform gyrus--FFA) and superior temporal sulcus (fSTS), but not the face-selective response in the occipital cortex (OFA), were highly correlated with the face-selective N170 component. In contrast, the OFA was correlated with earlier ERPs at about 110 ms after stimulus-onset. Importantly, these correlations reveal a temporal dissociation between the face-selective area in the occipital lobe and face-selective areas in the temporal lobe. Despite the very different time-scale of the fMRI and EEG signals, our data show that a correlation analysis across subjects may be informative with respect to the latency in which different brain regions process information.
使用功能磁共振成像（fMRI）和事件相关电位（ERP）测量方法，在人类中可靠地发现了一种选择性针对面部的神经信号，这两种方法为神经反应的空间和时间特性提供了互补信息。然而，由于迄今为止大多数神经影像学研究都分别研究了 ERP 和 fMRI 的面部选择性标记，因此它们之间的关系仍然未知。在这里，我们同时记录了面部和椅子的 fMRI 和 ERP 反应，以检查跨被试的 fMRI 和 ERP 面部选择性测量之间的相关性。研究结果表明，颞叶（即梭状回-FFA）和颞上沟（fSTS）中的选择性面孔反应，但不是枕叶皮层（OFA）中的选择性面孔反应，与选择性 N170 成分高度相关。相比之下，OFA 与刺激开始后约 110 毫秒的早期 ERP 相关。重要的是，这些相关性揭示了枕叶中的选择性面部区域与颞叶中的选择性面部区域之间的时间分离。尽管 fMRI 和 EEG 信号的时间尺度非常不同，但我们的数据表明，跨被试的相关分析可能与不同脑区处理信息的潜伏期有关。
