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金激光对鸡胚绒毛尿囊膜的影响。

Effects of Gold laser on the avian chorioallantoic membrane.

作者信息

Rees Catherine J, Allen Jacqueline, Postma Gregory N, Belafsky Peter C

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California Davis School of Medicine, Sacramento, California, USA.

出版信息

Ann Otol Rhinol Laryngol. 2010 Jan;119(1):50-3. doi: 10.1177/000348941011900110.

Abstract

OBJECTIVES

Office-based lasers have revolutionized the treatment of laryngeal disease. The 980-nm Gold laser is a device that may offer some practical advantages over other office lasers. The chick chorioallantoic membrane has been proposed as a model for predicting the effects of photoangiolytic lasers on vocal fold microvasculature. We sought to evaluate the effects of the Gold laser in this model.

METHODS

Vascular reactions in first-order vessels were determined for the Gold laser with both 0 degree straight and 30 degrees angled laser fibers. Vessels were treated at 15 W and a 500-ms pulse interval, with a 1-mm working distance. Pulse widths of 300 ms and 500 ms were evaluated. All vessels were treated until selective coagulation or vessel rupture.

RESULTS

We performed 60 trials on 30 embryos. The mean energy delivered was 33.7 J for the straight fiber and 51.2 J for the angled fiber. The laser achieved selective vessel coagulation without rupture in 100% (30 of 30) of straight fiber trials and in 100% (30 of 30) of angled fiber trials. In 6.7% (2 of 30) of straight fiber and 10% (3 of 30) of angled fiber trials, it caused minor injury to the surrounding albumin as indicated by white coagulum outside the vessel.

CONCLUSIONS

The Gold laser effectively coagulates small vessels without rupture at a working distance of 1 mm and settings of 15 W, 500-ms pulse interval, and 300- to 500-ms pulse width.

摘要

目的

基于办公室的激光技术彻底改变了喉部疾病的治疗方式。980纳米金激光是一种可能比其他办公室用激光具有一些实际优势的设备。鸡胚绒毛尿囊膜已被提议作为预测光血管溶解激光对声带微血管系统影响的模型。我们试图评估金激光在该模型中的效果。

方法

使用0度直激光纤维和30度角激光纤维对金激光的一级血管中的血管反应进行测定。在15瓦、500毫秒脉冲间隔和1毫米工作距离下对血管进行治疗。评估了300毫秒和500毫秒的脉冲宽度。对所有血管进行治疗,直至出现选择性凝血或血管破裂。

结果

我们对30个胚胎进行了60次试验。直纤维的平均输送能量为33.7焦耳,角纤维为51.2焦耳。在100%(30次中的30次)的直纤维试验和100%(30次中的30次)的角纤维试验中,激光实现了选择性血管凝血且未破裂。在6.7%(30次中的2次)的直纤维试验和10%(30次中的3次)的角纤维试验中,如血管外白色凝块所示,激光对周围白蛋白造成了轻微损伤。

结论

在1毫米工作距离、15瓦、500毫秒脉冲间隔和300至500毫秒脉冲宽度的设置下,金激光能有效凝固小血管且不破裂。

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