Wong Ian Y H, Yuen Nancy S Y, Chan Clement W N
Department of Ophthalmology, Tung Wah Eastern Hospital, Causeway Bay, Hong Kong.
Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb;41(1):96-9. doi: 10.3928/15428877-20091230-17.
After a single unilateral acute primary angle-closure glaucoma attack, retinal nerve fiber layer (RNFL) may be thinned. The current study measured the RNFL thickness using optical coherence tomography in eyes with normal visual fields after recovery from a single attack of acute primary angle-closure glaucoma.
Twenty-one patients and age-matched control subjects underwent optical coherence tomography scanning after recovery from a single unilateral acute primary angle-closure glaucoma attack. Data from the affected eyes, normal fellow eyes, and control subjects were compared.
Average RNFL thickness was 91.3 +/- 16.4 microm in the affected eyes, 100.1 +/- 16.4 microm in the fellow eyes, and 100.2 +/- 16.7 microm in the control eyes. Significant thinning was present in the affected eyes compared to the fellow eyes (P = .001) and the control eyes (P = .04).
RNFL thickness was found to be significantly thinner in the eyes with angle-closure glaucoma.
单次单侧急性原发性闭角型青光眼发作后,视网膜神经纤维层(RNFL)可能变薄。本研究采用光学相干断层扫描技术测量单次急性原发性闭角型青光眼发作恢复后视野正常的眼睛的RNFL厚度。
21例患者及年龄匹配的对照者在单次单侧急性原发性闭角型青光眼发作恢复后接受光学相干断层扫描。比较患眼、对侧正常眼及对照者的数据。
患眼的平均RNFL厚度为91.3±16.4微米,对侧眼为100.1±16.4微米,对照眼为100.2±16.7微米。与对侧眼(P = 0.001)和对照眼(P = 0.04)相比,患眼出现明显变薄。
发现闭角型青光眼患者的眼睛中RNFL厚度明显变薄。