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在巴西居住的日本移民群体的 12 个 X-STR 遗传数据。

Genetic data of twelve X-STRs in a Japanese immigrant population resident in Brazil.

机构信息

Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, Pará, Brazil.

出版信息

Forensic Sci Int Genet. 2010 Feb;4(2):e57-8. doi: 10.1016/j.fsigen.2009.05.004. Epub 2009 Jun 26.

Abstract

In the last years, several works have been published on the variability of X-markers; however, few were on Asian populations. In this work, we present the genetic data of 12 X-STRs (DXS9895, DXS7132, DXS6800, DXS9898, DXS6789, DXS7133, GATA172D05, DXS7130, HPRTB, GATA31E08, DXS7423, DXS10011) obtained from a sample of 232 individuals of Japanese origin residing in Brazil. Most markers investigated present a high genetic diversity, with the exception of DXS6800. No deviations from Hardy-Weinberg equilibrium were observed, with the exception of DXS7133 locus. Linkage disequilibrium analysis did not reveal consistent evidence of association between the X-STRs used. The comparison of the Japanese immigrant population with other Asian populations (Japanese, Chinese, and Korean) demonstrates the inexistence of significant allelic frequency differences between these populations in most systems investigated.

摘要

在过去的几年中,已经有几篇关于 X 标记变异性的论文发表;然而,针对亚洲人群的研究却很少。在这项工作中,我们呈现了来自巴西的 232 名日本裔个体的 12 个 X-STRs(DXS9895、DXS7132、DXS6800、DXS9898、DXS6789、DXS7133、GATA172D05、DXS7130、HPRTB、GATA31E08、DXS7423、DXS10011)的遗传数据。大多数研究的标记都表现出较高的遗传多样性,除了 DXS6800。除了 DXS7133 位点外,没有观察到偏离 Hardy-Weinberg 平衡。连锁不平衡分析没有发现所使用的 X-STR 之间存在一致的关联证据。与其他亚洲人群(日本、中国和韩国)的日本移民群体进行比较,结果表明在大多数研究的系统中,这些群体之间不存在显著的等位基因频率差异。

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