巴西东南部四个群体的 10 个 X-STR 遗传特征分析。
Genetic profile characterization of 10 X-STRs in four populations of the southeastern region of Brazil.
机构信息
Laboratório de Investigação de Paternidade, Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, Rodovia Araraquara-Jaú, Km 01, 14801-902, Araraquara, São Paulo, Brazil.
出版信息
Int J Legal Med. 2010 Sep;124(5):427-32. doi: 10.1007/s00414-010-0478-9. Epub 2010 Jun 16.
Ten X-chromosomal short tandem repeats (DXS8378, DXS9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7133, GATA172D05, GATA31E08 and DXS7423) were analyzed in four populations of the southeastern region of Brazil (São Paulo, Rio de Janeiro, Vitória and Belo Horizonte). No deviations from the Hardy-Weinberg equilibrium were observed for any of the analyzed loci in the four populations. The average diversity per locus varied between 68% for DXS8378, DXS7133, and DXS7423 and 83%, for DXS6809, with Rio de Janeiro being the most diverse population. Overall power of discrimination values in females varied between 0.99999999990 and 0.99999999997 and between 0.9999991 and 0.9999995 in males. These high values show the potential of this system for forensic application and relationships' testing in the studied groups. Genetic comparisons (exact tests of population differentiation and pairwise genetic distances) revealed significant differences between Brazilian and other populations from Europe, Latin America and Africa, as well as among different Brazilian populations.
对巴西东南部四个地区（圣保罗、里约热内卢、维多利亚和贝洛奥里藏特）的四个群体进行了 10 个 X 染色体短串联重复序列（DXS8378、DXS9902、DXS7132、DXS9898、DXS6809、DXS6789、DXS7133、GATA172D05、GATA31E08 和 DXS7423）的分析。在所分析的四个群体中，没有观察到任何一个分析位点偏离哈迪-温伯格平衡。每个位点的平均多样性在 68%（DXS8378、DXS7133 和 DXS7423）到 83%（DXS6809）之间，里约热内卢是最具多样性的群体。女性的总体鉴别力值在 0.99999999990 到 0.99999999997 之间，男性在 0.9999991 到 0.9999995 之间。这些高值表明该系统在研究群体中的法医应用和亲属关系测试具有潜力。遗传比较（种群分化的精确检验和成对遗传距离）显示了巴西与欧洲、拉丁美洲和非洲以及巴西不同地区之间的显著差异。
Zotero 插件