高度区分性基因座 DYS449、DYS481、DYS518、DYS612、DYS626、DYS644 和 DYS710 的特征分析。
Characterization of the highly discriminatory loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710.
机构信息
University of the Western Cape, Cape Town, South Africa.
出版信息
Forensic Sci Int Genet. 2010 Feb;4(2):104-10. doi: 10.1016/j.fsigen.2009.06.011. Epub 2009 Jul 29.
During the study of genetic diversity at non-core Y-STRs in South African population groups, we identified loci with high discrimination capacity. In this study we present a detailed account of the allele diversity, allele sequence data, gene diversity, allele frequency spectrum and informativeness for assignment in the European English, Asian Indian and Xhosa population groups at loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710. The suitability of these loci for forensic, genealogical and evolutionary studies is discussed, and nomenclature for loci DYS518, DYS612, DYS626 and DYS644 is suggested.
在研究南非人群中非核心 Y-STR 的遗传多样性时，我们鉴定了具有高判别能力的基因座。在本研究中，我们详细介绍了欧洲英语、亚洲印度人和科萨人群中 DYS449、DYS481、DYS518、DYS612、DYS626、DYS644 和 DYS710 基因座的等位基因多样性、等位基因序列数据、基因多样性、等位基因频率谱以及用于分配的信息量。讨论了这些基因座在法医学、家谱学和进化研究中的适用性，并建议了 DYS518、DYS612、DYS626 和 DYS644 基因座的命名法。
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