Aurora Health Care, West Allis, Wisconsin, USA.
Int J Gynaecol Obstet. 2010 May;109(2):140-3. doi: 10.1016/j.ijgo.2009.11.023. Epub 2010 Feb 2.
To ascertain the likelihood of identifying small for gestational age (SGA) neonates prenatally (below the 10th percentile for gestational age).
On admission for delivery, the charts of singletons with reliable gestational age (GA) were reviewed to determine whether intrauterine growth restriction (IUGR) was suspected, clinically or sonographically. Multiple logistic regression analysis was used with the accurate identification of SGA as the dependent variable and 13 independent variables.
Over 10 months, 1502 pregnant women met the inclusion criteria and 16% of neonates were born SGA. Before delivery, only 10% (95% confidence interval 6%-14%) of newborns identified as SGA were detected, and 7% weighed below the 5th percentile. Multiple logistic regression analysis identified 4 factors that made a significant independent contribution to the detection of SGA: younger maternal age, size less than date, sonographic examination within 4 weeks of delivery, and a history of substance abuse.
Because we failed to identify 90% of SGA with fundal height measurements, the likelihood of detecting most growth-restricted fetuses clinically is low. If other investigators confirm these findings, a paradigm shift is warranted to improve the detection of IUGR.
确定产前(低于胎龄的第 10 百分位数)识别小于胎龄儿(SGA)的可能性。
在分娩入院时,回顾具有可靠胎龄(GA)的单胎妊娠图表,以确定是否存在宫内生长受限(IUGR),无论是临床还是超声检查。使用多变量逻辑回归分析,将准确识别 SGA 作为因变量,有 13 个独立变量。
在 10 个月的时间里,1502 名孕妇符合纳入标准,其中 16%的新生儿出生时为 SGA。在分娩前,只有 10%(95%置信区间 6%-14%)被识别为 SGA 的新生儿被检测到,7%的新生儿体重低于第 5 百分位数。多变量逻辑回归分析确定了 4 个对 SGA 检测有显著独立贡献的因素:母亲年龄较小、小于胎龄、分娩前 4 周内进行超声检查、滥用物质史。
由于我们未能通过宫底高度测量识别 90%的 SGA,因此临床上检测到大多数生长受限胎儿的可能性较低。如果其他研究人员证实了这些发现,就有必要转变观念,以提高 IUGR 的检测率。