National Addiction Centre, Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.
Alcohol Alcohol. 2010 Mar-Apr;45(2):136-42. doi: 10.1093/alcalc/agq005.
To compare treatment outcomes between clients preferring abstinence and those preferring non-abstinence at the screening stage of a randomized controlled trial of treatment for alcohol problems (the United Kingdom Alcohol Treatment Trial) and to interpret any differential outcome in light of baseline differences between goal preference groups outlined in an accompanying paper.
Outcomes at 3 and 12 months' follow-up were recorded both in categorical terms (abstinence/non-problem drinking/much improved/somewhat improved/same/worse) and on continuous measures (percent days abstinent, drinks per drinking day/dependence score).
Clients initially stating a preference for abstinence showed a better outcome than those stating a preference for non-abstinence. This superior outcome was clearer at 3 months' follow-up but still evident at 12 months' follow-up. The better outcome consisted almost entirely in a greater frequency of abstinent days, with only a modest benefit in drinking intensity for goal abstainers that disappeared when baseline covariates of goal preference were controlled for. Type of successful outcome (abstinence/non-problem drinking) was related to initial goal preference, with clients preferring abstinence more likely to obtain an abstinent outcome and those preferring non-abstinence a non-problem drinking outcome.
The client's personal drinking goals should be discussed in assessment at treatment entry and as a basis for negotiation. Clinicians should be prepared to identify and support goal change as an unexceptional part of the treatment process that need not jeopardize good outcome.
比较在酒精问题治疗的随机对照试验(英国酒精治疗试验)的筛选阶段,选择戒酒和非戒酒的患者的治疗结果,并根据伴随文件中概述的目标偏好组的基线差异,解释任何差异结果。
在 3 个月和 12 个月的随访中,使用分类术语(戒酒/非问题饮酒/明显改善/有所改善/相同/恶化)和连续测量(戒酒天数百分比、每天饮酒量/依赖评分)记录结果。
最初表示偏好戒酒的患者比表示偏好非戒酒的患者表现出更好的结果。这种更好的结果在 3 个月的随访中更为明显,但在 12 个月的随访中仍然存在。更好的结果几乎完全是由于戒酒天数的增加,而对于戒酒目标的患者,饮酒强度的适度改善,当控制目标偏好的基线协变量时,这种改善就消失了。成功结果的类型(戒酒/非问题饮酒)与初始目标偏好有关,更喜欢戒酒的患者更有可能获得戒酒的结果,而更喜欢非戒酒的患者则更有可能获得非问题饮酒的结果。
在治疗开始时的评估和作为协商的基础上,应该讨论患者的个人饮酒目标。临床医生应该准备好识别和支持目标变化,作为治疗过程中一个正常的部分,而不会危及良好的结果。