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牛分枝杆菌椎间盘炎作为膀胱内卡介苗治疗的并发症。

Mycobacterium bovis discitis as a complication of intravesical Bacillus Calmette-Guérin therapy.

机构信息

Department of Rheumatology, Christchurch Hospital, Christchurch, United Kingdom.

出版信息

J Clin Rheumatol. 2010 Mar;16(2):74-5. doi: 10.1097/RHU.0b013e3181d070ea.

Abstract

We report a culture-proven case of Mycobacterium bovis discitis in a 67-year-old man who had received intravesical Bacillus Calmette-Guérin for bladder cancer 5 years previously. He presented with severe low back pain, and imaging revealed features of discitis and paraspinal abscesses. On aspiration of the abnormal tissue, culture confirmed infection with M. bovis. Quadruple antituberculous therapy was commenced at this stage, with a subsequent good clinical response. Hematogenous spread of M. bovis is a rare, often delayed, complication of intravesical BCG therapy, but early appropriate treatment can result in a good prognosis.

摘要

我们报告了一例经培养证实的牛分枝杆菌椎间盘炎病例,患者为 67 岁男性,5 年前因膀胱癌接受了膀胱内卡介苗治疗。他表现为严重的腰痛,影像学显示椎间盘炎和椎旁脓肿的特征。异常组织抽吸物培养证实感染了牛分枝杆菌。在这一阶段开始了四联抗结核治疗,随后临床反应良好。牛分枝杆菌血行播散是膀胱内卡介苗治疗的一种罕见且常延迟的并发症,但早期适当的治疗可以获得良好的预后。

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