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呼吸道感染相关微生物在可降解热塑性复合材料上的黏附

Adhesion of respiratory-infection-associated microorganisms on degradable thermoplastic composites.

作者信息

Tirri Teemu, Söderling Eva, Malin Minna, Peltola Matti, Seppälä Jukka V, Närhi Timo O

机构信息

Department of Prosthetic Dentistry and Biomaterials Science, Institute of Dentistry, University of Turku, 20520 Turku, Finland.

出版信息

Int J Biomater. 2009;2009:765813. doi: 10.1155/2009/765813. Epub 2009 Apr 6.

DOI:10.1155/2009/765813
PMID:20130804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2814101/
Abstract

The purpose of this study was to evaluate bacterial adhesion and early colonization on a composite consisting of bioactive glass (BAG) particles and copolymer of epsilon-caprolactone/D,L-lactide. Materials were incubated with suspensions of both type strains and clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa for 30 minutes (adhesion) and 4 hours (colonization). Clear differences exist in the microorganisms' ability to adhere on the experimental materials. However, the presence of BAG particles does not inhibit bacterial adhesion, but early colonization of the materials with P. aeruginosa was inhibited by the addition of 90-315 mum BAG particles.

摘要

本研究的目的是评估生物活性玻璃（BAG）颗粒与ε-己内酯/D，L-丙交酯共聚物组成的复合材料上的细菌粘附和早期定植情况。将材料与肺炎链球菌、流感嗜血杆菌和铜绿假单胞菌的标准菌株及临床分离株的悬液孵育30分钟（粘附）和4小时（定植）。微生物在实验材料上的粘附能力存在明显差异。然而，BAG颗粒的存在并不抑制细菌粘附，但添加90 - 315微米的BAG颗粒可抑制材料被铜绿假单胞菌的早期定植。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/69f7929335da/IJBM2009-765813.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/510f398b6b92/IJBM2009-765813.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/5f8602dc11fc/IJBM2009-765813.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/69f7929335da/IJBM2009-765813.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/510f398b6b92/IJBM2009-765813.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/5f8602dc11fc/IJBM2009-765813.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d001/2814101/69f7929335da/IJBM2009-765813.003.jpg

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