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[献血人群中的恰加斯病筛查]

[Chagas disease screening in the blood donor population].

作者信息

Assal A, Pelletier B, David B, Tiberghien P

机构信息

Etablissement français du sang, 20, avenue du Stade-de-France, F-93218 La-Plaine Saint-Denis cedex, France.

出版信息

Bull Soc Pathol Exot. 2009 Dec;102(5):291-4.

PMID:20131422
Abstract

In May 2007, the French Blood Service (Etablissement français du sang, EFS) introduced systematic screening of at-risk blood donors for anti-Trypanosoma cruzi antibodies. This concerned donors originating from an endemic area, donors with mothers originating from such an area and individuals who had lived in or travelled to endemic areas, whatever the length of their stay. Five samples out of 163,740 were positive, all from individuals originating from an endemic area. One thousand three hundred seventy-four blood donations were considered as equivocal because they had discordant results on the two Elisa tests used in screening. The authors discuss difficulties presented by routine screening of travellers and residents as well as the advantages and drawbacks of the strategy used. They present arguments in favour of its simplification.

摘要

2007年5月,法国血液服务机构(法国血液中心,EFS)开始对有风险的献血者进行系统性的克氏锥虫抗体筛查。这涉及来自流行地区的献血者、母亲来自此类地区的献血者以及曾在流行地区居住或旅行过的个人,无论其停留时间长短。在163,740份样本中有5份呈阳性,均来自来自流行地区的个人。1374份献血被视为结果不明确,因为它们在筛查中使用的两种酶联免疫吸附测定(ELISA)测试中结果不一致。作者讨论了对旅行者和居民进行常规筛查所面临的困难以及所采用策略的优缺点。他们提出了支持简化该策略的论据。

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1
[Chagas disease screening in the blood donor population].[献血人群中的恰加斯病筛查]
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[Detection of antibodies against Trypanosoma cruzi in blood donors].[献血者中克氏锥虫抗体的检测]
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