Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
J Am Chem Soc. 2010 Mar 3;132(8):2510-1. doi: 10.1021/ja910187s.
Highly reactive rhodium(II) N-trifluoromethylsulfonyl azavinyl carbenes are formed in situ from NH-1,2,3-triazoles, triflic anhydride, and rhodium carboxylates. They rapidly and selectively react with olefins, providing cyclopropane carboxaldehydes and 2,3-dihydropyrroles in generally excellent yields and high enantio- and diastereoselectivity.
高反应性的铑(II)N-三氟甲磺酰基氮杂环丁烯基卡宾可由 NH-1,2,3-三唑、三氟甲磺酸酐和铑羧酸酯原位形成。它们快速且选择性地与烯烃反应,通常以优异的收率和高对映选择性和非对映选择性提供环丙烷羧醛和 2,3-二氢吡咯。